ArticleBiology of sport2017
Variations in leptin, nesfatin-1 and irisin levels induced by aerobic exercise in young trained and untrained male subjects.
Article in Biology of sport, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exercise training mode effects on myokine expression in healthy adults: A systematic review with meta-analysis.Journal of sport and health science · 2024Pooled it
- Comparative Impact of Various Exercises on Circulating Irisin in Healthy Subjects: A Systematic Review and Network Meta-Analysis.Oxidative medicine and cellular longevity · 2022Pooled it
- Phase-dependent changes in serum kisspeptin and irisin levels across the menstrual cycle in healthy women.Journal of endocrinological investigation · 2026Article
- The Influence of Irisin on Selected Organs-The Liver, Kidneys, and Lungs: The Role of Physical Exercise.Cells · 2025Review
- Exercise as a multitarget therapy: modulating myokines, neurotrophins, and inflammation in Parkinson's disease.Frontiers in aging neuroscience · 2025Review
- The molecular signaling of exercise and obesity in the microbiota-gut-brain axis.Frontiers in endocrinology · 2022Review
- Combined Effects of High-Intensity Aerobic Exercise Training andFrontiers in endocrinology · 2022Article
- Fndc5/irisin is regulated by myogenesis stage, irisin, muscle type and training.American journal of translational research · 2022Article
- The effects of spirulina under high-intensity interval training on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females: A randomized, controlled, single-blind trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Irisin/FNDC5: A participant in camel metabolism.Saudi journal of biological sciences · 2021Article
- Effect of Acute Sprint Exercise on Myokines and Food Intake Hormones in Young Healthy Men.International journal of molecular sciences · 2020Article
- A Randomized Controlled Trial on the Effects of 12 Weeks of Aerobic, Resistance, and Combined Exercises Training on the Serum Levels of Nesfatin-1, Irisin-1 and HOMA-IR.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims of this study were to investigate the impacts of acute aerobic exercise on circulating levels of hormones associated with energy metabolism, namely leptin, nesfatin-1 and irisin, in trained and untrained male subjects and to determine whether the timing of the exercise (i.e. morning or night) amplified these impacts. Thirty trained (19.2±0.7 years) and 30 untrained (19.5±0.6 years) male subjects performed two aerobic running exercises (3 days between tests) to 64-76% of the subjects' maximal heart rate for about 30 min. Pre- and post-exercise venous blood samples were taken and analysed for leptin, nesfatin-1 and irisin using enzyme-linked immunosorbent assay (ELISA). Paired samples and independent samples t-tests were used to analyse data. Irisin levels increased in all the subjects (p<0.001). In both groups, nesfatin-1 levels increased significantly after the night-time exercise (p<0.05). Importantly, leptin and nesfatin-1 levels varied among the trained and untrained groups: Both leptin and nesfatin-1 levels increased in 4 (13%) and 12 (40%) subjects, respectively, after the morning exercises, and they increased in 9 (30%) and 10 (33%) subjects, respectively, after the night-time exercise. They decreased in 5 (16%) and 7 (23%) subjects, respectively, after the morning exercise and in 6 (20%) and 3 (10%) subjects, respectively, after the night-time exercise. Exercise may result in increased energy consumption by altering irisin levels. However, due to variations among individuals, increasing leptin and nesfatin-1 levels by reducing food intake may not be applicable.
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