Evidence map›Paper›PMID 29472584›Full record

ArticleNature communications2018

The structure of iPLA

Konstantin R Malley, Olga Koroleva, Ian Miller, Ruslan Sanishvili, Christopher M Jenkins, Richard W Gross, Sergey Korolev

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Clinical and genetic characteristics ofJournal of medical genetics · 2025
    Pooled it
  2. Phospholipases: Where Do We Stand?Methods in molecular biology (Clifton, N.J.) · 2027
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Association of Novel Pathogenic Variant (p. Ile366Asn) inInternational journal of molecular sciences · 2025
    Article
  13. Review
  14. The mechanism of allosteric regulation of calcium-independent phospholipase AProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Review
  17. Iron metabolism and ferroptosis in nonalcoholic fatty liver disease: what is our next step?American journal of physiology. Endocrinology and metabolism · 2024
    Review
  18. A rare inherited homozygous missense variant inTranslational pediatrics · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantin R MalleyEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, 63104, USA.
Olga KorolevaEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, 63104, USA.
Ian MillerEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, 63104, USA.
Ruslan SanishviliGM/CA@APS, Advanced Photon Source, Argonne National Laboratory, Argonne, IL, 60439, USA.
Christopher M JenkinsDivision of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8020, Saint Louis, MO, 63110, USA.
Richard W GrossDivision of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8020, Saint Louis, MO, 63110, USA.
Sergey KorolevEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, 63104, USA. sergey.korolev@health.slu.edu.ORCID http://orcid.org/0000-0001-9313-7126

Funding

REGULATION OF MYOCARDIAL PHOSPHOLIPASES AND LIPASES IN DIABETIC MYOCARDIUMR01HL118639 · NHLBI · WASHINGTON UNIVERSITY · PI GROSS, RICHARD W · 2013 to 2025
$9.1M
NOVEL LIPID 2ND MESSENGERS REGULATING BIOENERGETICS AND SIGNALING IN HUMAN MYOCARDIUMR01HL133178 · NHLBI · WASHINGTON UNIVERSITY · PI GROSS, RICHARD W · 2016 to 2024
$3.8M
Structural studies of PARK14R21NS094854 · NINDS · SAINT LOUIS UNIVERSITY · PI KOROLEV, SERGEY · 2016 to 2017
$417k
NHLBI NIH HHS R01 HL118639NHLBI NIH HHS R01 HL133178NINDS NIH HHS R21 NS094854
6 · The paper itself

Abstract

Calcium-independent phospholipase A

Indexed as

CalmodulinCatalytic DomainCrystallizationDimerizationGene Expression RegulationGroup VI Phospholipases A2HumansProtein BindingProtein TransportCalmodulinGroup VI Phospholipases A2

Identifiers

PMID29472584
PMCPMC5823874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.