Evidence map›Paper›PMID 29472414›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Laminin-521 Protein Therapy for Glomerular Basement Membrane and Podocyte Abnormalities in a Model of Pierson Syndrome.

Meei-Hua Lin, Joseph B Miller, Yamato Kikkawa, Hani Y Suleiman, Karl Tryggvason, Bradley L Hodges, Jeffrey H Miner

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Treatment Approaches for Alport Syndrome.Journal of the American Society of Nephrology : JASN · 2026
    Review
  3. Progress in skin gene therapy: From the inside and out.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  4. [Research progress on monogenic inherited glomerular diseases with central nervous system symptoms].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  5. The Protective Role of KANK1 in Podocyte Injury.International journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Current and Future Therapeutical Options in Alport Syndrome.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. The Pathology Lesion Patterns of Podocytopathies: How and why?Frontiers in cell and developmental biology · 2022
    Review
  13. Article
  14. Article
  15. Complexities of the glomerular basement membrane.Nature reviews. Nephrology · 2021
    Review
  16. Review
  17. Imaging the kidney: from light to super-resolution microscopy.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Review
  18. Review
  19. Article
  20. Endothelial cell-specific collagen type IV-αAmerican journal of physiology. Renal physiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Meei-Hua LinDivision of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Joseph B MillerDivision of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Yamato KikkawaDepartment of Clinical Biochemistry, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
Hani Y SuleimanDivision of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Karl TryggvasonCardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore.
Bradley L HodgesProthelia Inc., Milford, Massachusetts.
Jeffrey H MinerDivision of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri; minerj@wustl.edu.
Washington University in St. Louis · USDuke-NUS Medical School · SGProthelia (United States) · USTokyo University of Pharmacy and Life Sciences · JP

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1M
STRUCTURE AND FUNCTION OF CD2AP IN THE KIDNEYR01DK058366 · NIDDK · WASHINGTON UNIVERSITY · PI MINER, JEFFREY H · 2000 to 2019
$6.8M
LAMININS AND GLOMERULAR FILTRATIONR01DK078314 · NIDDK · WASHINGTON UNIVERSITY · PI MINER, JEFFREY H · 2008 to 2021
$5.4M
NIDDK NIH HHS P30 DK020579NIDDK NIH HHS R01 DK058366NIDDK NIH HHS R01 DK078314
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Abnormalities, MultipleAnimalsDesminDisease Models, AnimalEye AbnormalitiesGlomerular Basement MembraneInjections, IntravenousLamininMiceMyasthenic Syndromes, CongenitalNephrotic SyndromePermeabilityPodocytesProteinuriaPupil DisordersRecombinant ProteinsDesminLamininlaminin 11 protein, humanlaminin beta2Recombinant Proteinsglomerular basement membraneglomerular filtration barrierlamininpodocyte

Identifiers

PMID29472414
PMCPMC5967757
OpenAlexW2792761476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.