Evidence map›Paper›PMID 29472380›Full record

GuidelineCirculation2018

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association.

Sharonne N Hayes, Esther S H Kim, Jacqueline Saw, David Adlam, Cynthia Arslanian-Engoren, Katherine E Economy, Santhi K Ganesh, Rajiv Gulati, Mark E Lindsay, Jennifer H Mieres and 6 more

3 registry-linked trialsOpen access · bronzeAbstract readPractice GuidelineReview
In one paragraph

Guideline in Circulation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 614 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
614citing papers in PubMed, 5 pooled it
85.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01427179 recruitingnot on this map

Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)

Typeobservational_patient_registrySponsorMayo ClinicRan2011 to 2030Enrolled2,000ConditionsSpontaneous Coronary Artery Dissection, SCAD
NCT01429727 recruitingnot on this map

The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

TypeobservationalSponsorMayo ClinicRan2011 to 2030Enrolled2,500ConditionsSpontaneous Coronary Artery Dissection, SCAD
NCT03941184 completednot on this map

Determining the Association Between Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

TypeobservationalSponsorMayo ClinicRan1995 to 2020Enrolled114ConditionsSCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
3 · Its place in the literature

Who cites it

614 citing papers in PubMed, 5 syntheses or guidelines pooled it, 1,192 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Review
  7. STEMI caused by spontaneous coronary artery dissection: prevalence, patient characteristics and outcomes.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article

554 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 4 countries.

Sharonne N Hayes
Esther S H Kim
Jacqueline Saw
David Adlam
Cynthia Arslanian-Engoren
Katherine E Economy
Santhi K Ganesh
Rajiv Gulati
Mark E Lindsay
Jennifer H Mieres
Sahar Naderi
Svati Shah
David E Thaler
Marysia S Tweet
Malissa J Wood
American Heart Association Council on Peripheral Vascular Disease; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Genomic and Precision Medicine; and Stroke Council
American Heart Association · USRajiv Gandhi University · IN

Funding

Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
British Heart Foundation PG/13/96/30608NICHD NIH HHS K12 HD065987
6 · The paper itself

Abstract

Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented.

Indexed as

American Heart AssociationCoronary Vessel AnomaliesCardiac Imaging TechniquesCardiovascular AgentsConsensusConservative TreatmentCoronary Artery BypassFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionPredictive Value of TestsPregnancyPrevalenceRisk AssessmentCardiovascular AgentsAHA Scientific Statementscoronary artery dissection, spontaneousfibromuscular dysplasiamyocardial infarctionwomen

Identifiers

PMID29472380
PMCPMC5957087
OpenAlexW2793577196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.