Evidence map›Paper›PMID 29472308›Full record

ArticleG3 (Bethesda, Md.)2018

Systematic Complex Haploinsufficiency-Based Genetic Analysis of

Virginia E Glazier, Thomas Murante, Kristy Koselny, Daniel Murante, Marisol Esqueda, Gina A Wall, Melanie Wellington, Chiung-Yu Hung, Anuj Kumar, Damian J Krysan

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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  5. ThebioRxiv : the preprint server for biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Virginia E GlazierDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Thomas MuranteDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Kristy KoselnyDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Daniel MuranteDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Marisol EsquedaDepartment of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.
Gina A WallDepartment of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.
Melanie WellingtonDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642.
Chiung-Yu HungDepartment of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.
Anuj KumarDepartment of Molecular, Cellular and Developmental Biology, University of Michigan 48109.
Damian J KrysanDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York, 14642 damian-krysan@uiowa.edu.ORCID 0000-0001-6330-3365
University of Rochester Medical Center · USTexas Center for Infectious Disease · USUniversity of Michigan–Ann Arbor · US

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
Large scale synthetic genetic analysis in Candida albicansR01AI098450 · NIAID · UNIVERSITY OF ROCHESTER · PI KRYSAN, DAMIAN J · 2012 to 2016
$1.9M
Enhancement of protective efficacy of Coccidioides vaccines by adjuvantsR21AI114762 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI HUNG, CHIUNG-YU · 2015 to 2016
$439k
NIAID NIH HHS R01 AI098450NIAID NIH HHS R21 AI114762NIGMS NIH HHS R25 GM060655
6 · The paper itself

Abstract

Genetic interaction analysis is a powerful approach to the study of complex biological processes that are dependent on multiple genes. Because of the largely diploid nature of the human fungal pathogen

Indexed as

AnimalsBiofilmsCandida albicansCandidiasisDisease Models, AnimalFungal ProteinsGene DeletionGene LibraryGene Regulatory NetworksHaploinsufficiencyHeterozygotePhenotypePlanktonPlasmidsTranscription FactorsVirulenceFungal ProteinsTranscription Factorsbiofilm formationCandida albicanscomplex haploinsufficiencydisseminated candidiasishaploinsufficiencyhyphal morphogenesis

Identifiers

PMID29472308
PMCPMC5873919
OpenAlexW2794223021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.