Evidence map›Paper›PMID 29472294›Full record

ArticleThe Journal of biological chemistry2018

Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria.

Jan Madacki, Françoise Laval, Anna Grzegorzewicz, Anne Lemassu, Monika Záhorszká, Michael Arand, Michael McNeil, Mamadou Daffé, Mary Jackson, Marie-Antoinette Lanéelle and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Jan MadackiFrom the Department of Biochemistry, Faculty of Natural Sciences, Comenius University, 842 15 Bratislava, Slovakia.
Françoise Lavalthe Tuberculosis & Infection Biology Department, Institut de Pharmacologie et de Biologie Structurale, CNRS, 31077 Toulouse, France.
Anna Grzegorzewiczthe Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, and.
Anne Lemassuthe Tuberculosis & Infection Biology Department, Institut de Pharmacologie et de Biologie Structurale, CNRS, 31077 Toulouse, France.
Monika ZáhorszkáFrom the Department of Biochemistry, Faculty of Natural Sciences, Comenius University, 842 15 Bratislava, Slovakia.
Michael Arandthe Institute of Pharmacology and Toxicology, University of Zürich, CH-8057 Zürich, Switzerland.
Michael McNeilthe Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, and.
Mamadou Dafféthe Tuberculosis & Infection Biology Department, Institut de Pharmacologie et de Biologie Structurale, CNRS, 31077 Toulouse, France.
Mary Jacksonthe Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, and.
Marie-Antoinette Lanéellethe Tuberculosis & Infection Biology Department, Institut de Pharmacologie et de Biologie Structurale, CNRS, 31077 Toulouse, France.
Jana KordulákováFrom the Department of Biochemistry, Faculty of Natural Sciences, Comenius University, 842 15 Bratislava, Slovakia, jana.kordulakova@uniba.sk.
Institut de Pharmacologie et de Biologie Structurale · FRColorado State University · USComenius University Bratislava · SKUniversity of Zurich · CH

Funding

Mode of Action of Thiorcarlide in Mycobacterium TuberculosisR01AI063054 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI JACKSON, MARY · 2005 to 2012
$2.4M
NIAID NIH HHS R01 AI063054
6 · The paper itself

Abstract

Mycolic acids are the hallmark of the cell envelope in mycobacteria, which include the important human pathogens

Indexed as

Cell WallEpoxide HydrolasesFatty AcidsLipid MetabolismLipidsMass SpectrometryMycobacteriumMycobacterium smegmatisMycobacterium tuberculosisMycolic AcidsEpoxide HydrolasesFatty AcidsLipidsMycolic Acidsbacterial cell envelopecell wallepoxide hydrolaseepoxymycolic acidfatty acid metabolismlipidmass spectrometry (MS)mycobacteriamycolic acids

Identifiers

PMID29472294
PMCPMC5892587
OpenAlexW2788317855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.