ArticleEBioMedicine2018
p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice.
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Article in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- IFI204 drives gasdermin D-mediated mitochondrial permeabilization to amplify neuronal pyroptosis in ischemic stroke.Journal of neuroinflammation · 2026Article
- Lifestyle shapes preclinical social and microglial deficits in an Alzheimer's disease mouse model.Molecular psychiatry · 2026Article
- High-Throughput Label-free Single-Cell Proteomics Enabled by Multicolumn NanoLC with a 5-min Cycle Time.Research square · 2025Article
- IFI204 RestrictsMicroorganisms · 2025Article
- IFI207, a young and fast-evolving protein, controls retroviral replication via the STING pathway.mBio · 2024Article
- Synthesis, Characterization, and Application of 2-((3-(Chloromethyl)-benzoyl)oxy)benzoic Acid: A Review.ACS omega · 2023Review
- sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death.Cell death & disease · 2022Article
- Impaired Glucocorticoid Receptor Signaling Aggravates Lung Injury after Hemorrhagic Shock.Cells · 2021Article
- Cytosolic and nuclear recognition of virus and viral evasion.Molecular biomedicine · 2021Review
- Structural mechanism of DNA recognition by the p204 HIN domain.Nucleic acids research · 2021Article
- Syk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages.Frontiers in immunology · 2021Article
- Activation and Immune Regulation Mechanisms of PYHIN Family During Microbial Infection.Frontiers in microbiology · 2021Review
- Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids.Immunity · 2020Review
- Quantitative Proteomics Reveals Docosahexaenoic Acid-Mediated Neuroprotective Effects in Lipopolysaccharide-Stimulated Microglial Cells.Journal of proteome research · 2020Article
- Cardiopulmonary Bypass Induces Acute Lung Injury via the High-Mobility Group Box 1/Toll-Like Receptor 4 Pathway.Disease markers · 2020Article
- Structural analysis of the HIN1 domain of interferon-inducible protein 204.Acta crystallographica. Section F, Structural biology communications · 2019Article
- Co-Delivery Of Dihydroartemisinin And HMGB1 siRNA By TAT-Modified Cationic Liposomes Through The TLR4 Signaling Pathway For Treatment Of Lupus Nephritis.International journal of nanomedicine · 2019Article
- Ifi204/p204, a new piece in the sepsis puzzle.Annals of translational medicine · 2018Article
- RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity.Scientific reports · 2018Article
- Syk promotes phagocytosis by inducing reactive oxygen species generation and suppressing SOCS1 in macrophage-mediated inflammatory responses.International journal of immunopathology and pharmacologyArticle
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Authors and funding
16 authors at 4 institutions in 3 countries.
Young-Su YiDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA; Department of Pharmaceutical Engineering, Cheongju University, Cheongju 28503, Republic of Korea.
Jinlong JianDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Elena Gonzalez-GugelDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Yong-Xiang ShiDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Jinan, China.
Qingyun TianDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Wenyu FuDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Aubryanna HettinghouseDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Wenhao SongDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Ronghan LiuDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Michun HeDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA.
Huabing QiDepartment of Rehabilitation Medicine, Center of Bone Metabolism and Repair (CBMR),Trauma Center, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Third Military Medical University, China.
Jing YangDepartment of Rehabilitation Medicine, Center of Bone Metabolism and Repair (CBMR),Trauma Center, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Third Military Medical University, China.
Xiaolan DuDepartment of Rehabilitation Medicine, Center of Bone Metabolism and Repair (CBMR),Trauma Center, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Third Military Medical University, China.
GuoZhi XiaoDepartment of Biology and Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Southern University of Science and Technology, Shenzhen 518055, China; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Lin ChenDepartment of Rehabilitation Medicine, Center of Bone Metabolism and Repair (CBMR),Trauma Center, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Third Military Medical University, China. Electronic address: linchen70@163.com.
Chuan-Ju LiuDepartment of Orthopaedic Surgery, New York University School of Medicine, New York, NY 10003, USA; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: chuanju.liu@nyumc.org.
New York University · USDaping Hospital · CNArmy Medical University · CNSouthern University of Science and Technology · CN
Funding
The immunological mechanism of PGRNs anti-inflammatory effect - Renewal - 1R01AR062207 · NIAMS · YALE UNIVERSITY · PI Chuanju Liu · 2012 to 2026
$5.6MThe Role of PGRN Growth Factor in Osteoarthritis. - Renewal - 1 - Revision - 2R01AR061484 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIU, CHUANJU · 2011 to 2020
$4.8MProgranulin: A Novel Gene in Gaucher DiseasesR01NS103931 · NINDS · YALE UNIVERSITY · PI Chuanju Liu, Ying Sun · 2017 to 2026
$4.3MNIAMS NIH HHS R01 AR061484NIAMS NIH HHS R01 AR062207NINDS NIH HHS R01 NS103931
Abstract
p204, a murine member of an interferon-inducible p200 family, was reported to recognize intracellular viral and bacterial DNAs, however, its role in the innate immunity in vivo remains unknown due to the lack of p204-deficient animal models. In this study we first generated the p204
Indexed as
Signal TransductionAnimalsCells, CulturedCytokinesGenotypeImmunity, InnateInflammasomesInflammation MediatorsInterferon-betaInterferon Regulatory Factor-3LipopolysaccharidesMacrophage ActivationMacrophagesMiceMice, KnockoutModels, BiologicalCytokinesIfi16 protein, mouseInflammasomesInflammation MediatorsInterferon-betaInterferon Regulatory Factor-3LipopolysaccharidesNF-kappa BNuclear ProteinsPhosphoproteinsToll-Like Receptor 4IFN-βInflammatory responsesLPSMacrophagesp204TLR4
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.