Trial reportJournal of substance abuse treatment2018
Approach bias modification for cannabis use disorder: A proof-of-principle study.
Trial report in Journal of substance abuse treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patterns of brain function associated with cannabis cue-reactivity in regular cannabis users: a systematic review of fMRI studies.Psychopharmacology · 2021Pooled it
- Approach With Caution: A Pilot Randomised Controlled Trial of Approach Bias Modification for People Undergoing Residential Treatment for Methamphetamine Use Disorder.Drug and alcohol review · 2026Trial
- A multi-site proof-of-concept investigation of computerized approach-avoidance training in adolescent cannabis users.Drug and alcohol dependence · 2018Trial
- Neurocognitive Deficits Associated with Gambling Behavior: A Systematic Review and Meta-analysis of Executive Function, Decision-making, Delay Discounting & Reward Sensitivity.Indian journal of psychological medicine · 2026Review
- Article
- Approach Bias Modification for reducing Co-Occurring Alcohol and cannabis use among treatment-seeking Adolescents: Protocol of a randomized controlled trial.Contemporary clinical trials communications · 2025Article
- A cross-cultural fMRI investigation of cannabis approach bias in individuals with cannabis use disorder.Addictive behaviors reports · 2023Article
- Article
- Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions .Dialogues in clinical neuroscience · 2020Review
- A randomized controlled trial of a virtual reality based, approach-avoidance training program for alcohol use disorder: a study protocol.BMC psychiatry · 2020Article
- Article
- Preliminary evidence that computerized approach avoidance training is not associated with changes in fMRI cannabis cue reactivity in non-treatment-seeking adolescent cannabis users.Drug and alcohol dependence · 2019Article
- A Roadmap for Integrating Neuroscience Into Addiction Treatment: A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine.Frontiers in psychiatry · 2019Review
- Mobile Phone Cognitive Bias Modification Research Platform for Substance Use Disorders: Protocol for a Feasibility Study.JMIR research protocols · 2018Article
- Impact of cannabis legalization on treatment and research priorities for cannabis use disorder.International review of psychiatry (Abingdon, England) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundMore effective treatments for cannabis use disorder (CUD) are needed. Evidence suggests that biases in cognitive processing of drug-related stimuli are central to the development and maintenance of addiction. The current study examined the feasibility and effect of a novel intervention - approach bias modification (ApBM) - on cannabis approach bias and cue-reactivity.
methodsA randomized, double-blind, sham-controlled proof-of-principle laboratory experiment investigated the effect of a four-session computerized ApBM training protocol on cannabis approach bias and cue-reactivity in non-treatment seeking adults age 18-65 with CUD (N = 33). ApBM procedures involved responding to cannabis or neutral stimuli using a computer joystick to model approach or avoidance behavior. Reactivity to tactile, olfactory, and auditory cue sets was assessed with physiological (blood pressure and heart rate) and subjective (cannabis craving) measures. Cannabis use was assessed via self-report.
resultsParticipants receiving ApBM showed blunted cannabis cue-induced craving at the end of training compared to those in the sham-ApBM condition (p = .05). A preliminary gender effect on cannabis use was also found; men receiving ApBM reported fewer cannabis use sessions per day at the end of training compared to women (p = .02), while there were no differences between men and women in the sham condition. ApBM did not attenuate cannabis approach bias following training.
conclusionPreliminary results indicate that ApBM may be efficacious in reducing cannabis cue-reactivity and improving cannabis use outcomes. While encouraging, the results should be interpreted with caution. Investigation of ApBM as an adjunct to psychosocial treatments for treatment-seeking adults with CUD is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.