Evidence map›Paper›PMID 29471880›Full record

ArticleJournal of neuroinflammation2018

[

Aileen Hoehne, Michelle L James, Israt S Alam, John A Ronald, Bernadette Schneider, Aloma D'Souza, Timothy H Witney, Lauren E Andrews, Haley C Cropper, Deepak Behera and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Radiosynthesis and Analysis of (S)-4-(3-[Molecular imaging and biology · 2023
    Article
  8. Review
  9. Article
  10. Radiology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Characterization ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  16. Article
  17. Review
  18. Antibody-Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases.Chembiochem : a European journal of chemical biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Aileen HoehneMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Michelle L JamesMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Israt S AlamMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
John A RonaldMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Bernadette SchneiderMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Aloma D'SouzaMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Timothy H WitneyMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Lauren E AndrewsMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Haley C CropperMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Deepak BeheraMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Gayatri GowrishankarMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Zhaoqing DingDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, 94305, USA.
Tony Wyss-CorayDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, 94305, USA.
Frederick T ChinMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Sandip BiswalMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA.
Sanjiv S GambhirMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Stanford, CA, 94305, USA. sgambhir@stanford.edu.
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe cystine/glutamate antiporter (xc-) has been implicated in several neurological disorders and, specifically, in multiple sclerosis (MS) as a mediator of glutamate excitotoxicity and proinflammatory immune responses. We aimed to evaluate an xc-specific positron emission tomography (PET) radiotracer, (4S)-4-(3-[

methodsExperimental autoimmune encephalomyelitis (EAE) was induced in C57BL/6 mice by subcutaneous injection of myelin oligodendrocyte glycoprotein (MOG

results[

conclusionThese data highlight the promise of [

Indexed as

Amino Acid Transport Systems, AcidicAmino Acid Transport System y+AnimalsCells, CulturedEncephalomyelitis, Autoimmune, ExperimentalFluorine RadioisotopesFluorodeoxyglucose F18GlutamatesHumansLeukocytes, MononuclearMiceMice, Inbred C57BLMultiple SclerosisPositron-Emission Tomography4-(3-fluoropropyl)glutamic acidAmino Acid Transport Systems, AcidicAmino Acid Transport System y+Fluorine-18Fluorine RadioisotopesFluorodeoxyglucose F18GlutamatesSlc7a11 protein, ratEAE miceFSPGMultiple sclerosisPETXc-

Identifiers

PMID29471880
PMCPMC5822551
OpenAlexW2793012925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.