ReviewGenome medicine2018
Endophenotypes in psychiatric disease: prospects and challenges.
Review in Genome medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Transdiagnostic Neurocognitive Endophenotypes for Schizophrenia, Bipolar I Disorder and a Broad Psychosis/Bipolar I Disorder Phenotype: A Mega-Analysis of Twin and Sibling Data.Schizophrenia bulletin · 2026Pooled it
- Systematic Review of Functional MRI Applications for Psychiatric Disease Subtyping.Frontiers in psychiatry · 2021Pooled it
- Associations of genetic variants with gene expression factors reveal biological pathways underlying complex traits.American journal of human genetics · 2026Article
- Impaired Contour Object Perception in Psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression.Biological psychiatry global open science · 2025Article
- Psychometrics of drift-diffusion model parameters derived from the Eriksen flanker task: Reliability and validity in two independent samples.Cognitive, affective & behavioral neuroscience · 2025Article
- Molecular genetic basis of the primary emotions in young adults: an exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways.Frontiers in pharmacology · 2025Article
- HERVs Endophenotype in Autism Spectrum Disorder: Human Endogenous Retroviruses, Specific Immunoreactivity, and Disease Association in Different Family Members.Microorganisms · 2024Review
- Integrating early life stress in neurological disease: advancing preventive neurology.BMJ mental health · 2024Review
- Impaired contour object perception in psychosis.medRxiv : the preprint server for health sciences · 2024Article
- Novel genome-wide associations for effort valuation and psychopathology in children and adults.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2024Article
- Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood.Psychological medicine · 2024Article
- Biomarker-Guided Tailored Therapy in Major Depression.Advances in experimental medicine and biology · 2024Review
- Can neurological soft signs and neurocognitive deficits serve as a combined endophenotype for Han Chinese with bipolar disorder?International journal of methods in psychiatric research · 2023Article
- Early Identification and Intervention in Pediatric Obsessive-Compulsive Disorder.Brain sciences · 2023Review
- The Concept of Resistance to Substance Use and a Research Approach: The Resist! Project.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2023Article
- Neurocognitive Endophenotypes for Eating Disorders: A Preliminary High-Risk Family Study.Brain sciences · 2023Article
- Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity.Neurobiology of stress · 2023Article
- Working memory and reaction time variability mediate the relationship between polygenic risk and ADHD traits in a general population sample.Molecular psychiatry · 2022Article
- Evaluating depression- and anxiety-like behaviors in non-human primates.Frontiers in behavioral neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Endophenotypes, quantitative neurobehavioral traits that index genetic susceptibility for a psychiatric disorder, have been examined in thousands of studies. Nevertheless, they have underexploited potential to provide etiological insights into prognosis, how psychopathology develops, the etiology of comorbidity, and the mechanisms of gene function.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.