Evidence map›Paper›PMID 29471839›Full record

ArticleTrials2018

Controlled Education of patients after Stroke (CEOPS)- nurse-led multimodal and long-term interventional program involving a patient's caregiver to optimize secondary prevention of stroke: study protocol for a randomized controlled trial.

Anne-Marie Mendyk, Alain Duhamel, Yannick Bejot, Didier Leys, Laurent Derex, Olivier Dereeper, Olivier Detante, Pierre-Yves Garcia, Olivier Godefroy, Francisco Macian Montoro and 10 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02132364 (Controlled Education Of Patients After Stroke), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02132364 nacompletednot on this map

Controlled Education Of Patients After Stroke

TypeinterventionalSponsorUniversity Hospital, LilleRan2014 to 2021Enrolled290ConditionsStroke, HypertensionArmsoptimised follow-up
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Information provision for stroke survivors and their carers.The Cochrane database of systematic reviews · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 11 institutions in 1 country.

Anne-Marie MendykUniversity Lille, Inserm, CHU, U1171 'Degenerative and vascular cognitive disorders', F-59000, Lille, France.
Alain DuhamelUniversity Lille, CHU, EA2694, F-59000, Lille, France.
Yannick BejotUniversity Hospital and Medical School of Dijon, University of Burgundy, Digon, France.
Didier LeysUniversity Lille, Inserm, CHU, U1171 'Degenerative and vascular cognitive disorders', F-59000, Lille, France.
Laurent DerexDepartment of Stroke Medicine, Université Lyon 1, Lyon, France.
Olivier DereeperStroke Unit, Neurology Department, Calais Hospital, Calais, France.
Olivier DetanteUniversité Grenoble Alpes, Grenoble Institut des Neurosciences, GIN, Grenoble, France.
Pierre-Yves GarciaStroke Unit, Neurology Department, Compiègne Hospital, Compiègne, France.
Olivier GodefroyDepartment of Neurology and Functional Neuroscience Laboratory EA 4559, Amiens University Medical Center, Amiens, France.
Francisco Macian MontoroStroke Unit, University Hospital of Limoges, Limoges, France.
Jean-Philippe NeauDepartment of Neurology, CHU of Poitiers, University of Poitiers, Poitiers, France.
Sébastien RichardStroke unit, Department of Neurology, CHU of Nancy, Lorraine University, Nancy, France.
Thierry RosolacciStroke Unit, Neurology Department, Maubeuge Hospital, Maubeuge, France.
Igor SibonDepartment of Neurology, Bordeaux University Hospital, University of Bordeaux, Bordeaux, France.
Denis SablotStroke Unit, Neurology Department, Perpignan Hospital, Perpignan, France.
Serge TimsitCHRU Brest, Department of Neurology and Stroke Unit, Université de Bretagne Occidentale, Brest, France.
Mathieu ZuberDepartment of Neurology, Saint-Joseph Hospital Center, AP - HP, Université Paris-Descartes, INSERM UMR S 919, Paris, France.
Charlotte CordonnierUniversity Lille, Inserm, CHU, U1171 'Degenerative and vascular cognitive disorders', F-59000, Lille, France.
Régis BordetUniversity Lille, Inserm, CHU, U1171 'Degenerative and vascular cognitive disorders', F-59000, Lille, France. regis.bordet@univ-lille2.fr.
on the behalf of Strokavenir network
Inserm · FRCentre Hospitalier Universitaire Amiens-Picardie · FRDélégation Paris 5 · FRUniversité Claude Bernard Lyon 1 · FRUniversité de Bordeaux · FRUniversité de Poitiers · FRCentre Hospitalier Compiègne-Noyon · FRGrenoble Institute of Neurosciences · FRUniversité de Bourgogne · FRUniversité de Bretagne Occidentale · FRUniversité de Lorraine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSetting up a follow-up secondary prevention program after stroke is difficult due to motor and cognitive impairment, but necessary to prevent recurrence and improve patients' quality of life. To involve a referent nurse and a caregiver from the patient's social circle in nurse-led multimodal and long-term management of risk factors after stroke could be an advantage due to their easier access to the patient and family. The aim of this study is to compare the benefit of optimized follow up by nursing personnel from the vascular neurology department including therapeutic follow up, and an interventional program directed to the patient and a caregiving member of their social circle, as compared with typical follow up in order to develop a specific follow-up program of secondary prevention of stroke. METHODS/

designThe design is a randomized, controlled, clinical trial conducted in the French Stroke Unit of the Strokavenir network. In total, 410 patients will be recruited and randomized in optimized follow up or usual follow up for 2 years. In both group, patients will be seen by a neurologist at 6, 12 and 24 months. The optimized follow up will include follow up by a nurse from the vascular neurology department, including therapeutic follow up, and a training program on secondary prevention directed to the patient and a caregiving member of their social circle. After discharge, a monthly telephone interview, in the first year and every 3 months in the second year, will be performed by the nurse. At 6, 12 and 24 month, the nurse will give the patient and caregiver another training session. Usual follow up is only done by the patient's general practitioner, after classical information on secondary prevention of risk factors during hospitalization. The primary outcome measure is blood pressure measured after the first year of follow up. Blood pressure will be measured by nursing personnel who do not know the group into which the patient has been randomized. Secondary endpoints are associated mortality, morbidity, recurrence, drug side-effects and medico-economic analysis. DISCUSSION: The result of this trial is expected to provide the benefit of a nurse-led optimized multimodal and long-term interventional program for management of risk factors after stroke, personalizing the role of the nurse and including the patient's caregiver.

trial registrationClinicalTrials.gov, NCT 02132364. Registered on 7 May 2014. EUDRACT, A 00473-40.

Indexed as

Nurse's RolePatient Care TeamCaregiversCombined Modality TherapyDisability EvaluationFranceHumansLeadershipNeurologic ExaminationPatient Education as TopicRandomized Controlled Trials as TopicRecovery of FunctionSecondary PreventionStrokeStroke RehabilitationTime FactorsFamily caregiverMultimodal interventionNurseSecondary preventionStroke

Identifiers

PMID29471839
PMCPMC5824577
OpenAlexW2806172547

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.