ArticleBMC genomics2018
Divergence and evolution of cotton bHLH proteins from diploid to allotetraploid.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 32 citations in OpenAlex.
- Genome-Wide Identification and Characterization of bHLH Family inLife (Basel, Switzerland) · 2026Article
- Genome-wide dissection ofHorticulture research · 2026Article
- Genetic Analysis of an FInternational journal of molecular sciences · 2024Article
- Genome-wide identification of the GRF family in sweet orange (Citrus sinensis) and functional analysis of the CsGRF04 in response to multiple abiotic stresses.BMC genomics · 2024Article
- Genome-Wide Identification and Characterization of thePlants (Basel, Switzerland) · 2023Article
- Regulatory and functional divergence among members ofFrontiers in plant science · 2023Article
- Transcriptome Time-Course Analysis in the Whole Period of Cotton Fiber Development.Frontiers in plant science · 2022Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPolyploidy is considered a major driving force in genome expansion, yielding duplicated genes whose expression may be conserved or divergence as a consequence of polyploidization.
resultsWe compared the genome sequences of tetraploid cotton (Gossypium hirsutum) and its two diploid progenitors, G. arboreum and G. raimondii, and found that the bHLH genes were conserved over the polyploidization. Oppositely, the expression of the homeolgous gene pairs was diversified. The biased homeologous proportion for bHLH family is significantly higher (64.6%) than the genome wide homeologous expression bias (40%). Compared with cacao (T. cacao), orthologous genes only accounted for a small proportion (41.7%) of whole cotton bHLHs family. The further Ks analysis indicated that bHLH genes underwent at least two distinct episodes of whole genome duplication: a recent duplication (1.0-60.0 million years ago, MYA, 0.005 < Ks < 0.312) and an old duplication (> 60.0 MYA, 0.312 < Ks < 3.0). The old duplication event might have played a key role in the expansion of the bHLH family. Both recent and old duplicated pairs (68.8%) showed a divergent expression profile, indicating specialized functions. The expression diversification of the duplicated genes suggested it might be a universal feature of the long-term evolution of cotton.
conclusionsOverview of cotton bHLH proteins indicated a conserved and divergent evolution from diploids to allotetraploid. Our results provided an excellent example for studying the long-term evolution of polyploidy.
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