Evidence map›Paper›PMID 29471764›Full record

ArticleInternational journal of STD & AIDS2018

Oropharyngeal HPV infection: prevalence and sampling methods among HIV-infected men in South Africa.

Admire Chikandiwa, Pedro T Pisa, Matthew F Chersich, Etienne E Muller, Philippe Mayaud, Sinead Delany-Moretlwe

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Oral HPV infection clearance and acquisition after nonavalent vaccination in men who have sex with men and transgender women: a prospective analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Epidemiology of HPV Related Malignancies.Seminars in radiation oncology · 2021
    Review
  11. Review
  12. Article
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Admire Chikandiwa1 Wits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-4954-2225
Pedro T Pisa1 Wits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Matthew F Chersich1 Wits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Etienne E Muller2 National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.
Philippe Mayaud1 Wits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Sinead Delany-Moretlwe1 Wits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Worldwide, 96,000 cases of oropharyngeal cancer (OPC) occurred in 2012. Human papillomavirus (HPV) is a risk factor for OPC. Data on oropharyngeal HPV infection are limited. There is no consensus on the best sampling method for detecting the infection. We describe the prevalence of oropharyngeal HPV infection among HIV-infected men and compare the performance of oral rinses and swabs in detecting oropharyngeal HPV infection. Paired oral rinses and swabs for 181 men were tested for HPV DNA using the Roche Linear Array. Performance was determined by the number of infections detected and the percentage of samples with adequate DNA extraction. Agreement between sampling methods was assessed by the kappa statistic. Prevalence of oropharyngeal HPV infection with rinse samples was 1.8% (three infections) and 0.6% (one infection) with swabs (p = 0.06). Adequate cellular DNA extraction was more likely with rinse (93.4%) than swab samples (89.0%, p = 0.05). There was moderate agreement between the methods (kappa = 0.49). The prevalence of oropharyngeal HPV DNA infection among this predominantly heterosexual sample of men living with HIV was low and consistent with the infrequent oral sex practices. Oral rinse performed better than oral swab in detecting oropharyngeal HPV DNA infection and might contribute to screening for OPCs.

Indexed as

HeterosexualitySexual BehaviorAdultCohort StudiesHIV InfectionsHumansMaleMiddle AgedMouthMouth NeoplasmsOropharyngeal NeoplasmsPapillomaviridaePapillomavirus InfectionsPrevalenceSouth AfricaYoung AdultAfricaHuman papillomavirusmenoral cavityoral sex

Identifiers

PMID29471764
PMCPMC6009177

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.