Evidence map›Paper›PMID 29471722›Full record

ArticleJournal of intensive care medicine2020

Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit.

Laura S Peterson, Cecilia Gállego Suárez, Hannah E Segaloff, Cameron Griffin, Emily T Martin, Folafoluwa O Odetola, Kanakadurga Singer

Abstract read
In one paragraph

Article in Journal of intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Obesity and immune status in children.Current opinion in pediatrics · 2020
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura S PetersonDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.
Cecilia Gállego SuárezDivision of Pediatric Endocrinology and Metabolism, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.
Hannah E SegaloffDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Cameron GriffinDivision of Pediatric Endocrinology and Metabolism, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.
Emily T MartinDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Folafoluwa O OdetolaDivision of Critical Care Medicine, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.
Kanakadurga SingerDivision of Pediatric Endocrinology and Metabolism, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Mechanisms of hematopoietic stem cell activation in obesityK08DK101755 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SINGER, KANAKADURGA · 2015 to 2018
$644k
NIDDK NIH HHS K08 DK101755NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

objectiveTo evaluate the effect of overweight and obesity on outcomes and resource use among patients with sepsis in the pediatric intensive care unit (PICU).

designRetrospective analysis of clinical characteristics, resource use, and mortality among children 0 to 20 years of age admitted to the C.S. MottChildren's Hospital PICU (University of Michigan) between January 2009 and December 2015, with a diagnostic code for sepsis at admission (based on MEASUREMENTS AND MAIN

resultsA total of 454 participants met the inclusion criteria. Seventy-six were categorized as underweight (body mass index [BMI] percentile <5th) and were excluded, which left a final sample size of 378 participants. Children with a BMI

conclusionsAlthough PICU mortality and length of stay were similar for obese-overweight patients and normal weight critically ill children with sepsis, there was significantly higher use of specialized organ-supportive technology among obese patients, likely indicating higher occurrence of multiple organ dysfunction.

Indexed as

Critical Care OutcomesBody Mass IndexChildChild, PreschoolCritical CareFacilities and Services UtilizationFemaleHumansInfantIntensive Care Units, PediatricLength of StayMaleOdds RatioPediatric ObesityRegression AnalysisRetrospective Studiesintensive care unitmorbiditymortalityobesityoverweightpediatricssepsis

Identifiers

PMID29471722
PMCPMC6027613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.