ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018
Assessing Viral Transfer During Doffing of Ebola-Level Personal Protective Equipment in a Biocontainment Unit.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Skin Problems in the Facial Area due to the Use of Personal Protective Equipment in Healthcare Workers: A Systematic Review.Journal of clinical nursing · 2025Pooled it
- Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff.The Cochrane database of systematic reviews · 2020Pooled it
- Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff.The Cochrane database of systematic reviews · 2020Pooled it
- Reusable respirators as personal protective equipment in clinical practice : User experience in times of a pandemic.Wiener klinische Wochenschrift · 2022Trial
- Effect of an Intervention Package and Teamwork Training to Prevent Healthcare Personnel Self-contamination During Personal Protective Equipment Doffing.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Trial
- Gastrointestinal symptoms associated with PPE use among nurses in COVID-19 wards: a cross-sectional study.Frontiers in public health · 2026Article
- Doffing procedures of personal protective equipment evaluated with lipid nanoparticles as viral surrogates: uncovering potential blind spots.Antimicrobial resistance and infection control · 2025Article
- Self-contamination risk and failure modes during high-level PPE doffing: A pilot comparison of 2 powered air-purifying respirator (PAPR) hoods.American journal of infection control · 2025Article
- Is there sufficient evidence to inform personal protective equipment choices for healthcare workers caring for patients with viral hemorrhagic fevers?Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025Article
- Is Personal Protective Equipment Worth the Hassle? Annual Risk of Cryptosporidiosis to Dairy Farmers and How Personal Protective Equipment and Handwashing Can Mitigate It.Microorganisms · 2023Article
- A narrative review of high-level isolation unit operational and infrastructure features.BMJ global health · 2023Review
- Bacterial contamination on used face masks among nursing home healthcare personnel.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Health care worker knowledge and attitudes towards uniform laundering during the COVID-19 pandemic.American journal of infection control · 2022Article
- Resilience and Protection of Health Care and Research Laboratory Workers During the SARS-CoV-2 Pandemic: Analysis and Case Study From an Austrian High Security Laboratory.Frontiers in psychology · 2022Review
- Modeling fomite-mediated SARS-CoV-2 exposure through personal protective equipment doffing in a hospital environment.Indoor air · 2022Article
- Coronavirus Pandemic - SARS-CoV-2 in Orthopedics and Trauma Surgery.Zeitschrift fur Orthopadie und Unfallchirurgie · 2021Article
- Dealing with the COVID-19 pandemic in orthopaedics: experiences and procedure in Germany.Bone & joint open · 2020Article
- Assessment of antibiotic-resistant organism transmission among rooms of hospitalized patients, healthcare personnel, and the hospital environment utilizing surrogate markers and selective bacterial cultures.Infection control and hospital epidemiology · 2020Article
- Common Behaviors and Faults When Doffing Personal Protective Equipment for Patients With Serious Communicable Diseases.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Effect of Glove Decontamination on Bacterial Contamination of Healthcare Personnel Hands.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
Background: Personal protective equipment (PPE) protects healthcare workers (HCWs) caring for patients with Ebola virus disease (EVD), and PPE doffing is a critical point for preventing viral self-contamination. We assessed contamination of skin, gloves, and scrubs after doffing Ebola-level PPE contaminated with surrogate viruses: bacteriophages MS2 and Φ6. Methods: In a medical biocontainment unit, HCWs (n = 10) experienced in EVD care donned and doffed PPE following unit protocols that incorporate trained observer guidance and alcohol-based hand rub (ABHR). A mixture of Φ6 (enveloped), MS2 (nonenveloped), and fluorescent marker was applied to 4 PPE sites, approximating body fluid viral load (Φ6, 105; MS2, 106). They performed a patient care task, then doffed. Inner gloves, face, hands, and scrubs were sampled for virus, as were environmental sites with visible fluorescent marker. Results: Among 10 HCWs there was no Φ6 transfer to inner gloves, hands, or face; 1 participant had Φ6 on scrubs at low levels (1.4 × 102). MS2 transfer (range, 101-106) was observed to scrubs (n = 2), hands (n = 1), and inner gloves (n = 7), where it was highest. Most (n = 8) had only 1 positive site. Environmental samples with visible fluorescent marker (n = 21) were negative. Conclusions: Among experienced HCWs, structured, observed doffing using ABHR protected against hand contamination with enveloped virus. Nonenveloped virus was infrequent on hands and scrubs but common on inner gloves, suggesting that inner gloves, but not necessarily ABHR, protect against hand contamination. Optimizing doffing protocols to protect against all types of viruses may require reinforcing careful handling of scrubs and good glove/hand hygiene with effective agents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.