ArticleSchizophrenia bulletin2018
Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective.
Article in Schizophrenia bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Clinical Assessment Interview for Negative Symptoms (CAINS): A Systematic Review of Measurement Properties.Schizophrenia bulletin · 2024Pooled it
- EPA guidance on assessment of negative symptoms in schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2021Pooled it
- Elevated Plasma DISC1 Levels Are Associated With Motivational Deficits in Medication-Free Patients With Major Depressive Disorder: An Exploratory Study.PsyCh journal · 2026Article
- Characterizing social motivation deficits in treatment-resistant schizophrenia: Evidence from social incentive performance.Psychiatry and clinical neurosciences · 2026Article
- Blunted Ventral Striatal Reactivity to Social Reward Is Associated with More Severe Motivation and Pleasure Deficits in Psychosis.Schizophrenia bulletin · 2025Article
- Motivation and Pleasure Domain Links to Social Function in College Students: A Network Analysis.PsyCh journal · 2025Article
- A transdiagnostic approach of negative symptoms in psychiatric disorders: replication of a two-factor structure in major depressive disorder and bipolar disorder.European archives of psychiatry and clinical neuroscience · 2025Article
- A Transdiagnostic Network Analysis of Childhood Trauma and Psychopathology.Schizophrenia bulletin · 2025Article
- Blunted ventral striatal reactivity to social reward is associated with more severe motivation and pleasure deficits in psychosis.Research square · 2024Article
- Reward motivation adaptation in people with negative schizotypal features: development of a novel behavioural paradigm and identifying its neural correlates using resting-state functional connectivity analysis.European archives of psychiatry and clinical neuroscience · 2024Article
- Negative symptoms in schizophrenia differ across environmental contexts in daily life.Journal of psychiatric research · 2023Article
- Bridge centrality network structure of negative symptoms in people with schizophrenia.European archives of psychiatry and clinical neuroscience · 2023Article
- Negative schizotypal traits predict the reduction of reward motivation in effort-reward imbalance.European archives of psychiatry and clinical neuroscience · 2023Article
- The Important Role of Motivation and Pleasure Deficits on Social Functioning in Patients With Schizophrenia: A Network Analysis.Schizophrenia bulletin · 2022Article
- Validation of accelerometry as a digital phenotyping measure of negative symptoms in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2022Article
- Validation of the French Clinical Assessment Interview for Negative Symptoms in a Sample of Stable French Individuals With Schizophrenia.Frontiers in psychiatry · 2022Article
- Cognitive, community functioning and clinical correlates of the Clinical Assessment Interview for Negative Symptoms (CAINS) in psychotic disorders.European archives of psychiatry and clinical neuroscience · 2021Article
- What is the Best Latent Structure of Negative Symptoms in Schizophrenia? A Systematic Review.Schizophrenia bulletin open · 2021Article
- Validation of the Chinese Version of the 16-Item Negative Symptom Assessment.Neuropsychiatric disease and treatment · 2020Article
- Personality Traits and Disorders in Adolescents at Clinical High Risk for Psychosis: Toward a Clinically Meaningful Diagnosis.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Clinical Assessment Interview for Negative Symptoms (CAINS) was designed in accordance with the recent theory and research in social affective neuroscience and to address the psychometric and conceptual limitations of other instruments assessing negative symptoms. The present study aimed to provide a large-scale validation of the CAINS in China and examine its applicability and validity evidence across the schizophrenia spectrum. Using confirmatory factor analysis, our results replicated the original findings in the US development samples that the CAINS possesses a stable 2-factor structure, namely "motivation/pleasure" and "expression". We also found significant correlations between the CAINS and other negative symptom measures. The CAINS demonstrated good discriminant validity in differentiating negative symptoms in people with schizophrenia, nonpsychotic first-degree relatives and people with social anhedonia. People with schizophrenia exhibited significantly higher CAINS subscale scores than first-degree relatives and healthy controls. In addition, first-degree relatives had higher "motivation/pleasure" scores than healthy controls. The "motivation/pleasure" subscale scores of individuals with social anhedonia were also significantly higher than healthy controls.
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