SynthesisAmerican journal of clinical pathology2018
Effectiveness of Practices to Support Appropriate Laboratory Test Utilization: A Laboratory Medicine Best Practices Systematic Review and Meta-Analysis.
Synthesis in American journal of clinical pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Laboratory Medicine Best Practices Systematic Review and Meta-analysis of Nucleic Acid Amplification Tests (NAATs) and Algorithms Including NAATs for the Diagnosis ofClinical microbiology reviews · 2019Pooled it
- Clinical decision support improves the appropriateness of laboratory test ordering in primary care without increasing diagnostic error: the ELMO cluster randomized trial.Implementation science : IS · 2020Trial
- Diagnostic stewardship perceptions and practices among microbiology laboratories: a national survey from the American Society for Microbiology.Journal of clinical microbiology · 2026Article
- Novel approach to the codesign of a tailored intervention bundle: applying theory with pragmatism.BMJ open quality · 2026Article
- Real-World Utilization Patterns of Toxoplasmosis Diagnostic Testing in Korea: A Large-Scale Laboratory-Based Study.Journal of clinical laboratory analysis · 2026Article
- Clinical laboratory diagnostic stewardship as boundary infrastructure: a multi-stakeholder qualitative study of digital public health governance in two Chinese regional referral hospitals.Frontiers in public health · 2026Article
- Targeting low-value laboratory care.Clinical chemistry and laboratory medicine · 2025Article
- Advancing diagnostic stewardship through claims-based utilization analysis: toward a system-wide vision of diagnostic excellence.Clinical chemistry and laboratory medicine · 2025Article
- Criteria for Routine Laboratory Blood Tests in Patients Hospitalized in Cardiology Departments.Diagnostics (Basel, Switzerland) · 2025Article
- Extending the Calgary Audit and Feedback Framework into the virtual environment: a process evaluation and empiric evidence.Implementation science communications · 2024Article
- Serum human epididymis Protein-4 outperforms conventional biomarkers in the early detection of non-small cell lung cancer.iScience · 2024Article
- The foundation for the microbiology laboratory's essential role in diagnostic stewardship: an ASM Laboratory Practices Subcommittee report.Journal of clinical microbiology · 2024Review
- Re-Purposing the Ordering of Routine Laboratory Tests in Hospitalized Medical Patients (RePORT): protocol for a multicenter stepped-wedge cluster randomised trial to evaluate the impact of a multicomponent intervention bundle to reduce laboratory test over-utilization.Implementation science : IS · 2024Article
- Do Laboratory Blood Tests Change Medical Care in Patients Hospitalized with Community-Acquired Pneumonia?Diagnostics (Basel, Switzerland) · 2024Article
- Interventions to improve appropriateness of laboratory testing in the intensive care unit: a narrative review.Annals of intensive care · 2024Review
- Managing Resource Utilization Cost of Laboratory Tests for Patients on Chemotherapy in Johns Hopkins Aramco Healthcare.Global journal on quality and safety in healthcare · 2023Article
- Systematic fungal biomarker or polymerase chain reaction testing in lung transplant recipients: Retrospective analysis to optimize their use.Transplant infectious disease : an official journal of the Transplantation Society · 2023Article
- Impact of computerised provider order entry on the quality and quantity of clinical information included with investigation requests: an interrupted time series analysis.BMJ open quality · 2023Article
- Investigating Investigation (Ab)Use: Thyroid Function Test Audit in a Tertiary Care Teaching Institute in Eastern India.Indian journal of clinical biochemistry : IJCB · 2022Article
- A Genomic Information Management System for Maintaining Healthy Genomic States and Application of Genomic Big Data in Clinical Research.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the effectiveness of practices used to support appropriate clinical laboratory test utilization.
methodsThis review followed the Centers for Disease Control and Prevention (CDC) Laboratory Medicine Best Practices A6 cycle method. Eligible studies assessed one of the following practices for effect on outcomes relating to over- or underutilization: computerized provider order entry (CPOE), clinical decision support systems/tools (CDSS/CDST), education, feedback, test review, reflex testing, laboratory test utilization (LTU) teams, and any combination of these practices. Eligible outcomes included intermediate, systems outcomes (eg, number of tests ordered/performed and cost of tests), as well as patient-related outcomes (eg, length of hospital stay, readmission rates, morbidity, and mortality).
resultsEighty-three studies met inclusion criteria. Fifty-one of these studies could be meta-analyzed. Strength of evidence ratings for each practice ranged from high to insufficient.
conclusionPractice recommendations are made for CPOE (specifically, modifications to existing CPOE), reflex testing, and combined practices. No recommendation for or against could be made for CDSS/CDST, education, feedback, test review, and LTU. Findings from this review serve to inform guidance for future studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.