ReviewNeuron2018
Neuromodulation of Attention.
Review in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
180 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of high-intensity interval training effects on cognitive function in older adults and cognitively impaired patients.Frontiers in physiology · 2025Pooled it
- Effect of muscarinic blockade on the speed of attention shifting, read-out delays and learning.Psychopharmacology · 2025Trial
- A causal role of the NMDA receptor in recurrent processing during perceptual integration.eLife · 2025Trial
- Pharmacological Manipulations of Physiological Arousal and Sleep-Like Slow Waves Modulate Sustained Attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Trial
- Biperiden Challenge Model in Healthy Elderly as Proof-of-Pharmacology Tool: A Randomized, Placebo-Controlled Trial.Journal of clinical pharmacology · 2021Trial
- Acetylcholine enhances deviance detection in Hodgkin-Huxley neuronal networks.Cognitive neurodynamics · 2026Article
- Dopamine modulation of motor and implicit learning contributions to auditory temporal attention.iScience · 2026Article
- A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- PDC-Net: A Prefrontal Dual-Channel Network with Gated Mamba Interaction for Cross-Subject Visual Attentional State Decoding.Brain sciences · 2026Article
- Nicotine causes highly localized and tuned changes in thalamocortical gain that cascade strongly and selectively through the cortical circuit.bioRxiv : the preprint server for biology · 2026Article
- Cognitive engagement induces area-specific fingerprints of dopamine, acetylcholine, serotonin, glutamate and GABA in prefrontal cortex and striatum.bioRxiv : the preprint server for biology · 2026Article
- Modeling attention and binding in the brain through bidirectional recurrent gating.Nature communications · 2026Article
- The neurovascular impulse response function differentially reflects intrinsic neuromodulation across cortical regions.Nature neuroscience · 2026Article
- Visual attention is linked to temporally structured noradrenaline release in the medial prefrontal cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Not simply two sides of the same coin: Target enhancement and distractor suppression draw on independent neural mechanisms.Attention, perception & psychophysics · 2026Article
- Effect of Dance Intervention on Cognitive Function and Related Cerebellar Dynamic Functional Connectivity in Patients With Schizophrenia.Alpha psychiatry · 2026Article
- Voluntary Attention Selectively Modulates Omission Responses.Human brain mapping · 2026Article
- EEG Unpredictability in the Resting State of Major Depressive Disorder: A Multidomain EEG Analysis.Brain topography · 2026Article
- Effects of Expectation, Attention, and NMDA Receptor Blockade on Feedforward and Feedback Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Rapid dynamics of dorsal raphe serotonin neurons regulate the strength of visual attention.Nature communications · 2026Article
120 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Attention is critical to high-level cognition and attention deficits are a hallmark of neurologic and neuropsychiatric disorders. Although years of research indicates that distinct neuromodulators influence attentional control, a mechanistic account that traverses levels of analysis (cells, circuits, behavior) is missing. However, such an account is critical to guide the development of next-generation pharmacotherapies aimed at forestalling or remediating the global burden associated with disorders of attention. Here, we summarize current neuroscientific understanding of how attention affects single neurons and networks of neurons. We then review key results that have informed our understanding of how neuromodulation shapes these neuron and network properties and thereby enables the appropriate allocation of attention to relevant external or internal events. Finally, we highlight areas where we believe hypotheses can be formulated and tackled experimentally in the near future, thereby critically increasing our mechanistic understanding of how attention is implemented at the cellular and network levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.