Evidence map›Paper›PMID 29470967›Full record

ArticleNeuron2018

A Spotlight on Appetite.

Lisa R Beutler, Zachary A Knight

Open access · bronzeAbstract read
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lisa R BeutlerDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA.
Zachary A KnightDepartment of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA; Kavli Center for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: zachary.knight@ucsf.edu.
University of California, San Francisco · US

Funding

UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Neural Dynamics Underlying FeedingR01DK106399 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Zachary A. Knight · 2015 to 2026
$4.8M
Sequencing Neural Circuits Controlling ThermoregulationDP2DK109533 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KNIGHT, ZACHARY A. · 2015 to 2015
$1.9M
Warm sensitive neurons that control body temperatureR01NS094781 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KNIGHT, ZACHARY A. · 2016 to 2020
$1.7M
NIDDK NIH HHS DP2 DK109533NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK106399NINDS NIH HHS R01 NS094781
6 · The paper itself

Abstract

Remarkably few hormones have been identified that stimulate appetite. The recent discovery of asprosin, a hormone that activates AgRP neurons to increase food intake and body weight, begins to fill this gap (Duerrschmid et al., 2017; Romere et al., 2016).

Indexed as

Appetite RegulationAdipokinesAgouti-Related ProteinAnimalsEatingFibrillin-1GhrelinHumansMice, TransgenicMicrofilament ProteinsNeuronsPeptide FragmentsPeptide HormonesAdipokinesAgouti-Related ProteinFBN1 protein, humanFibrillin-1GhrelinMicrofilament ProteinsPeptide FragmentsPeptide Hormones

Identifiers

PMID29470967
PMCPMC5965268
OpenAlexW2789060251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.