ReviewAnnals of biomedical engineering2018
Nitinol Stents in the Femoropopliteal Artery: A Mechanical Perspective on Material, Design, and Performance.
Review in Annals of biomedical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05643989 (Randomized Non-inferiority Single-center Prospective Trial of Malignant Colonic Obstruction Therapy With Self-expandable Metal Stent), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Non-inferiority Single-center Prospective Trial of Malignant Colonic Obstruction Therapy With Self-expandable Metal Stent (SEMS) Endoscopic Placement or Stoma Formation.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Performance of stenting in femoropopliteal disease: a systematic literature review and meta-analysis of proportions.Journal of comparative effectiveness research · 2026Pooled it
- Paclitaxel-Coated versus Uncoated Balloon for Femoropopliteal In-Stent Restenosis: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2022Pooled it
- Cardiovascular stent technologies for coronary and valvular heart disease: the potential of 3D printing for stent fabrication.Nature reviews. Cardiology · 2026Review
- Biomechanical Characterization of Porcine Lower Limb Arteries for Preclinical Evaluation of Peripheral Vascular Devices.Annals of biomedical engineering · 2026Article
- State-of-the-Art Review on Finite Element Analysis Applied to Ultrathin-Strut Drug-Eluting Stents: Examining the Present and Looking Ahead to the Future.Bioengineering (Basel, Switzerland) · 2026Review
- Numerical Evaluation of a Zero Poisson's Ratio Structure in µ-3D-Printed Self-Expanding Nitinol Stents.Micromachines · 2026Article
- The Influence of Stent-Strut Morphology on Iliac Limb Hemodynamics During EVAR in Compliant 3D-Printed Arterial Models.Journal of clinical medicine · 2026Article
- Computational Optimization of a Stent for the Femoropopliteal Artery.Annals of biomedical engineering · 2026Article
- Splanchnic vein reconstruction using dedicated venous stents.Journal of vascular surgery cases and innovative techniques · 2026Article
- Exploring the Complexities of Bone Implants and Stents: Factors Influencing Successful Tissue Integration.Advances in experimental medicine and biology · 2026Review
- BIOMECHANICAL CHARACTERIZATION OF PORCINE LOWER LIMB ARTERIES FOR PRECLINICAL EVALUATION OF PERIPHERAL VASCULAR DEVICES.bioRxiv : the preprint server for biology · 2025Article
- NITINOL MATERIAL PROPERTIES OF 11 COMMERCIAL PERIPHERAL STENTS DETERMINED USING INVERSE COMPUTATIONAL ANALYSIS.bioRxiv : the preprint server for biology · 2025Article
- Article
- Woven solutions for tissue engineering: Next-generation heart valves from fiber to function.American heart journal plus : cardiology research and practice · 2025Article
- Article
- Manufacturing, Processing, and Characterization of Self-Expanding Metallic Stents: A Comprehensive Review.Bioengineering (Basel, Switzerland) · 2024Review
- Structural and Mechanical Properties of Human Superficial Femoral and Popliteal Arteries.Annals of biomedical engineering · 2024Review
- Smart Biomaterials in Biomedical Applications: Current Advances and Possible Future Directions.Macromolecular bioscience · 2024Review
- Design and use of an ex vivo peripheral simulating bioreactor system for pharmacokinetic analysis of a drug coated stent.Bioengineering & translational medicine · 2024Article
- The CathCam: A Novel Angioscopic Solution for Endovascular Interventions.Annals of biomedical engineering · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Endovascular stenting has matured into a commonly used treatment for peripheral arterial disease (PAD) due to its minimally invasive nature and associated reductions in short-term morbidity and mortality. The mechanical properties of the superelastic Nitinol alloy have played a major role in the explosion of peripheral artery stenting, with modern stents demonstrating reasonable resilience and durability. Yet in the superficial femoral and popliteal arteries, even the newest generation Nitinol stents continue to demonstrate clinical outcomes that leave significant room for improvement. Restenosis and progression of native arterial disease often lead to recurrence of symptoms and reinterventions that increase morbidity and health care expenditures. One of the main factors thought to be associated with stent failure in the femoropopliteal artery (FPA) is the unique and highly dynamic mechanical environment of the lower limb. Clinical and experimental data demonstrate that the FPA undergoes significant deformations with limb flexion. It is hypothesized that the inability of many existing stent designs to conform to these deformations likely plays a role in reconstruction failure, as repetitive movements of the leg and thigh combine with mechanical mismatch between the artery and the stent and result in mechanical damage to both the artery and the stent. In this review we will identify challenges and provide a mechanical perspective of FPA stenting, and then discuss current research directions with promise to provide a better understanding of Nitinol, specific features of stent design, and improved characterization of the biomechanical environment of the FPA to facilitate development of better stents for patients with PAD.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.