Evidence map›Paper›PMID 29470615›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2018

Pre-dosing with lilotomab prior to therapy with

Caroline Stokke, Johan Blakkisrud, Ayca Løndalen, Jostein Dahle, Anne C T Martinsen, Harald Holte, Arne Kolstad

Abstract readClinical Trial, Phase IClinical Trial, Phase II
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. FDG PET/CT and Dosimetric Studies ofMolecular imaging and biology · 2022
    Trial
  2. Trial
  3. Review
  4. Article
  5. A Phase II Study ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Scientific reports · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline StokkeDepartment of Diagnostic Physics, Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway. carsto@ous-hf.no.ORCID 0000-0003-4465-9635
Johan BlakkisrudDepartment of Diagnostic Physics, Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Ayca LøndalenDivision of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Jostein DahleNordic Nanovector ASA, Oslo, Norway.
Anne C T MartinsenDepartment of Diagnostic Physics, Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Harald HolteDepartment of Oncology, Radiumhospitalet, Oslo University Hospital, Oslo, Norway.
Arne KolstadDepartment of Oncology, Radiumhospitalet, Oslo University Hospital, Oslo, Norway.

Funding

Helse Sør-Øst RHF 2017041/Stokke
6 · The paper itself

Abstract

purpose

methodsTwo of the phase 1 arms included cold lilotomab pre-dosing (arm 1 and 4; 40 mg fixed and 100 mg/m

resultsOrgans with distinct uptake of

conclusionsRM is the primary dose-limiting organ for

Indexed as

RadioimmunotherapyAdultAgedAged, 80 and overAntibodies, MonoclonalBone MarrowFemaleHumansLymphoma, Non-HodgkinMiddle AgedNeoplasm Recurrence, LocalRadiometryRadiotherapy DosageTissue DistributionAntibodies, Monoclonal177Lu-lilotomab satetraxetanAntibody radionuclide conjugate therapyDosimetryMolecular radiotherapyNon-Hodgkin lymphomaRadioimmunotherapy

Identifiers

PMID29470615
PMCPMC5953993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.