Evidence map›Paper›PMID 29470164›Full record

ArticleEmerging infectious diseases2018

External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil.

Carlo Fischer, Celia Pedroso, Alfredo Mendrone, Ana Maria Bispo de Filippis, Antonio Carlos Rosário Vallinoto, Bergmann Morais Ribeiro, Edison Luiz Durigon, Ernesto T A Marques, Gubio S Campos, Isabelle F T Viana and 17 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. External quality assessment of SARS-CoV-2 serology in European expert laboratories, April 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Early Clinical Infancy Outcomes for Microcephaly and/or Small for Gestational Age Zika-Exposed Infants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  16. Article
  17. Observational
  18. Toscana, West Nile, Usutu and tick-borne encephalitis viruses: external quality assessment for molecular detection of emerging neurotropic viruses in Europe, 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Carlo Fischer
Celia Pedroso
Alfredo Mendrone
Ana Maria Bispo de Filippis
Antonio Carlos Rosário Vallinoto
Bergmann Morais Ribeiro
Edison Luiz Durigon
Ernesto T A Marques
Gubio S Campos
Isabelle F T Viana
José Eduardo Levi
Luciano Cesar Scarpelli
Mauricio Lacerda Nogueira
Michele de Souza Bastos
Nathalia C Santiago Souza
Ricardo Khouri
Sanny Lira
Shirley Vasconcelos Komninakis
Cécile Baronti
Rémi N Charrel
Beate M Kümmerer
Christian Drosten
Carlos Brites
Xavier de Lamballerie
Matthias Niedrig
Eduardo Martins Netto
Jan Felix Drexler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is needed to adequately estimate risk for Zika virus-associated disease and determine patient care.

Indexed as

BrazilHumansLaboratoriesMolecular Diagnostic TechniquesQuality ControlRNA, ViralSensitivity and SpecificityViral LoadZika VirusRNA, ViralAmericasBrazildiagnosticsreal-time RT-PCRsurveillancevector-borne infectionsvirusesZika virus

Identifiers

PMID29470164
PMCPMC5938781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.