Observational studyJournal of veterinary internal medicine2018
Effects of Diagnostic Work-Up on Medical Decision-Making for Canine Urinary Tract Infection: An Observational Study in Danish Small Animal Practices.
Observational study in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- A Review of Fluoroquinolones with a Focus on Veterinary-Approved Agents.Biomolecules · 2026Review
- Urinary neutrophil gelatinase-associated lipocalin in dogs: accuracy of a novel rapid test and biomarker behavior across clinical settings.Journal of veterinary internal medicine · 2026Article
- Prevalence and Antimicrobial Resistance Trends of Canine Uropathogens in a Veterinary Teaching Hospital in Northern Italy: A 10-Year Retrospective Study (2014-2023).Veterinary sciences · 2025Article
- Antimicrobial Resistance in Companion Animals: A 30-Month Analysis on Clinical Isolates from Urinary Tract Infections in a Veterinary Hospital.Animals : an open access journal from MDPI · 2025Article
- Mitigating antimicrobial resistance, an approach to stewardship in canine urinary tract infection.Veterinary research communications · 2024Article
- Predictive phage therapy forProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Patient weight has diverse effects on the prescribing of different antibiotics to dogs.Frontiers in veterinary science · 2024Article
- Prevalence and Antimicrobial Resistance of Bacterial Uropathogens Isolated from Dogs and Cats.Antibiotics (Basel, Switzerland) · 2022Article
- In Vitro Killing of Canine Urinary Tract Infection Pathogens by Ampicillin, Cephalexin, Marbofloxacin, Pradofloxacin, and Trimethoprim/Sulfamethoxazole.Microorganisms · 2021Article
- How Accurate Are Veterinary Clinicians Employing Flexicult Vet for Identification and Antimicrobial Susceptibility Testing of Urinary Bacteria?Antibiotics (Basel, Switzerland) · 2021Article
- Evaluation of antimicrobial prescriptions in dogs with suspected bacterial urinary tract disease.Journal of veterinary internal medicine · 2021Article
- Antibiotic Stewardship for Canine and Feline Acute Urinary Tract Infection: An Observational Study in a Small Animal Hospital in Northwest Italy.Antibiotics (Basel, Switzerland) · 2021Article
- Antimicrobial Prescribing Practices in Dogs and Cats by Colombian Veterinarians in the City of Medellin.Veterinary sciences · 2021Article
- Transurethral cystoscopy in dogs with recurrent urinary tract infections: Retrospective study (2011-2018).Journal of veterinary internal medicine · 2020Article
- Antimicrobial prescriptions and adherence to prudent use guidelines for selected canine diseases in Switzerland in 2016.Veterinary record open · 2020Article
- Article
- The Occurrence of Multidrug Resistant Bacteria in the Urine of Healthy Dogs and Dogs with Cystitis.Animals : an open access journal from MDPI · 2019Article
- Antimicrobial use for selected diseases in cats in Switzerland.BMC veterinary research · 2019Article
- Prevalence of bacteria and changes in trends in antimicrobial resistance ofVeterinary record open · 2019Article
- Evaluation of a rapid immunoassay for bacteriuria in dogs.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical signs of urinary tract disease in dogs often lead to prescription of antibiotics. Appropriate diagnostic work-up could optimize treatment and reduce the risk of inappropriate use of antibiotics. HYPOTHESIS/
objectivesTo describe and evaluate the impact of diagnostic work-up on decision to treat (DTT) and choice of antibiotic treatment (COT) for dogs presenting with clinical signs of urinary tract disease. ANIMALS: One hundred and fifty-one dogs presenting to 52 Danish veterinary practices.
methodsProspective, observational study. Clinical signs, diagnostic work-up, and prescriptions were recorded. Urine samples were submitted to a reference laboratory for quantitative bacterial culture (QBC) and susceptibility testing. The laboratory results were used as reference for assessing the appropriateness of DTT and COT.
resultsIn the majority of dogs, veterinarians performed dipstick (99%), microscopic examination of urine (80%) and bacterial culture (56%). Fifty-one percent of dogs had urinary tract infection (UTI) based on reference QBC. Appropriate DTT was made for 62% of the dogs, while 36% were over-prescribed and 2% under-prescribed. Inappropriate use of second-line agents was found in 57% of the UTI cases. Performing microscopy-but not culture-significantly impacted DTT (P = 0.039) while no difference was seen in COT (P = 0.67). The accuracy of in-house microscopy and culture were 64.5 and 77%, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE: Over-prescription of antibiotics was common among dogs with suspected UTI, regardless of the diagnostic work-up performed. Test inaccuracy under practice conditions and incoherence between diagnostic test results and decision-making both explained inappropriate and unnecessary use of antibiotics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.