Evidence map›Paper›PMID 29469937›Full record

ArticleJournal of magnetic resonance imaging : JMRI2018

Radiomic features on MRI enable risk categorization of prostate cancer patients on active surveillance: Preliminary findings.

Ahmad Algohary, Satish Viswanath, Rakesh Shiradkar, Soumya Ghose, Shivani Pahwa, Daniel Moses, Ivan Jambor, Ronald Shnier, Maret Böhm, Anne-Maree Haynes and 9 more

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ahmad AlgoharyDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID http://orcid.org/0000-0003-1286-3164
Satish ViswanathDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Rakesh ShiradkarDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Soumya GhoseDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Shivani PahwaDepartment of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
Daniel MosesGarvan Institute of Medical Research, Sydney, Australia.ORCID http://orcid.org/0000-0001-9404-0035
Ivan JamborDepartment of Diagnostic Radiology, University of Turku, Turku, Finland.
Ronald ShnierGarvan Institute of Medical Research, Sydney, Australia.
Maret BöhmGarvan Institute of Medical Research, Sydney, Australia.
Anne-Maree HaynesGarvan Institute of Medical Research, Sydney, Australia.
Phillip BrennerDepartment of Urology, St. Vincent's Hospital, Sydney, Australia.
Warick DelpradoDouglass Hanly Moir Pathology, Sydney, Australia.
James ThompsonGarvan Institute of Medical Research, Sydney, Australia.
Marley PulbrockGarvan Institute of Medical Research, Sydney, Australia.
Andrei S PuryskoSection of Abdominal Imaging and Nuclear Radiology Department, Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-6888-0417
Sadhna VermaDepartment of Radiology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Lee PonskyDepartment of Urology, Case Western Reserve University, Cleveland, Ohio, USA.
Phillip StrickerDepartment of Urology, St. Vincent's Hospital, Sydney, Australia.
Anant MadabhushiDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.

Funding

Computerized histologic image predictor of cancer outcomeR01CA202752 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FELDMAN, MICHAEL D, GANESAN, SHRIDAR · 2016 to 2020
$3.1M
Computerized Histologic Risk Predictor (CHiRP) for Early Stage Lung CancersR01CA216579 · NCI · EMORY UNIVERSITY · PI FU, PINGFU, LLOYD, MARK · 2018 to 2023
$3.1M
MR Fingerprinting and Computerized Decision Support for Prostate CancerR01CA208236 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GULANI, VIKAS, PONSKY, LEE EVAN · 2017 to 2022
$3.0M
Pathology Image Informatics Platform for visualization, analysis and managementU24CA199374 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GURCAN, METIN NAFI, MADABHUSHI, ANANT · 2015 to 2019
$2.9M
Histologic image-based aggressiveness prediction in p16+ oropharyngeal carcinomaR21CA179327 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MADABHUSHI, ANANT · 2014 to 2015
$389k
Computerized morphologic-molecular predictor of progression in DCISR21CA195152 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI BADVE, SUNIL S., MADABHUSHI, ANANT · 2015 to 2016
$388k
NCI NIH HHS R01 CA202752NCI NIH HHS R01 CA208236NCI NIH HHS R01 CA216579NCI NIH HHS R21 CA179327NCI NIH HHS R21 CA195152NCI NIH HHS U24 CA199374
6 · The paper itself

Abstract

backgroundRadiomic analysis is defined as computationally extracting features from radiographic images for quantitatively characterizing disease patterns. There has been recent interest in examining the use of MRI for identifying prostate cancer (PCa) aggressiveness in patients on active surveillance (AS). PURPOSE: To evaluate the performance of MRI-based radiomic features in identifying the presence or absence of clinically significant PCa in AS patients. STUDY TYPE: Retrospective. SUBJECTS MODEL: MRI/TRUS (transperineal grid ultrasound) fusion-guided biopsy was performed for 56 PCa patients on AS who had undergone prebiopsy. FIELD STRENGTH/SEQUENCE: 3T, T ASSESSMENT: A pathologist histopathologically defined the presence of clinically significant disease. A radiologist manually delineated lesions on T STATISTICAL TESTS: Wilcoxon rank-sum tests with P < 0.05 considered statistically significant.

resultsSeven T DATA

conclusionRadiomic features could help in identifying the presence and absence of clinically significant disease in AS patients when PIRADS v2.0 assessment on MRI contradicted pathology findings of MRI-TRUS prostate biopsies. LEVEL OF EVIDENCE: 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018.

Indexed as

active surveillanceMRIprostate cancerradiomic featuresradiomicstexture features

Identifiers

PMID29469937
PMCPMC6105554

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.