Evidence map›Paper›PMID 29469805›Full record

ArticleeLife2018

C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation.

Chang Hoon Lee, Hongwei H Zhang, Satya P Singh, Lily Koo, Juraj Kabat, Hsinyi Tsang, Tej Pratap Singh, Joshua M Farber

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
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  15. Article
  16. Article
  17. MAIT cells and the microbiome.Frontiers in immunology · 2023
    Review
  18. MAIT cells in liver inflammation and fibrosis.Seminars in immunopathology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Chang Hoon Lee *Inflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.ORCID https://orcid.org/0000-0001-8953-9069
Hongwei H Zhang *Inflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.ORCID http://orcid.org/0000-0001-7298-8802
Satya P SinghInflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Lily KooBiological Imaging Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Juraj KabatBiological Imaging Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Hsinyi TsangInflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Tej Pratap SinghInflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Joshua M FarberInflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.ORCID http://orcid.org/0000-0003-3224-0378
National Institutes of Health · US

Funding

Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1M
Activities Of Chemokines In VivoZIAAI000725 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FARBER, JOSHUA M · 2009 to 2025
$25.5M
NIAID NIH HHS Intramural Research Program
6 · The paper itself

Abstract

Many mediators and regulators of extravasation by bona fide human memory-phenotype T cells remain undefined. Mucosal-associated invariant T (MAIT) cells are innate-like, antibacterial cells that we found excelled at crossing inflamed endothelium. They displayed abundant selectin ligands, with high expression of

Indexed as

Cell CommunicationAnimalsbeta-Galactoside alpha-2,3-SialyltransferaseCCAAT-Enhancer-Binding Protein-deltaCell MovementCells, CulturedEndothelial CellsFlow CytometryFucosyltransferasesGene ExpressionHumansMice, Inbred C57BLMucosal-Associated Invariant T CellsReceptors, CCR2Receptors, CCR6Sialyltransferasesbeta-Galactoside alpha-2,3-SialyltransferaseCCAAT-Enhancer-Binding Protein-deltaCcr2 protein, mouseCCR6 protein, mouseCEBPD protein, humanFucosyltransferasesfucosyltransferase VII, mouseReceptors, CCR2Receptors, CCR6SialyltransferaseschemokineextravasationhumanimmunologyinflammationmouseT celltranscription factors

Identifiers

PMID29469805
PMCPMC5869018
OpenAlexW2788170114

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.