Evidence map›Paper›PMID 29469590›Full record

SynthesisAging & mental health2019

Association of physical functioning of persons with dementia with caregiver burden and depression in dementia caregivers: an integrative data analysis.

Nicole M Armstrong, Laura N Gitlin, Jeanine M Parisi, David L Roth, Alden L Gross

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Aging & mental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicole M Armstronga Department of Epidemiology , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.ORCID 0000-0002-2479-1076
Laura N Gitlinc Division of Geriatrics and Gerontology, Department of Medicine , Johns Hopkins School of Medicine , Baltimore , MD , USA.
Jeanine M Parisid Center For Innovative Care in Aging , Johns Hopkins School of Nursing , Baltimore , MD USA.
David L Rotha Department of Epidemiology , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Alden L Grossa Department of Epidemiology , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Johns Hopkins University · US

Funding

EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
Improving Outcomes for Family Caregivers and Older Adults with Complex Conditions: The Adult Day Service Plus ProgramR01AG049692 · NIA · JOHNS HOPKINS UNIVERSITY · PI GAUGLER, JOSEPH E., GITLIN, LAURA N. · 2016 to 2020
$4.9M
Reducing Agitation in Dementia Patients at Home: The Customized Activity TrialR01AG041781 · NIA · JOHNS HOPKINS UNIVERSITY · PI GITLIN, LAURA N. · 2012 to 2017
$3.3M
Reducing Family Caregiver Upset with Disruptive BehaviorR01AG022254 · NIA · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2002 to 2006
$2.7M
COORDINATING CENTER FOR ENHANCING ADRD CAREGIVINGU01AG013305 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHULZ, RICHARD · 1995 to 2003
$2.5M
Multisite Intervention Trial for Diverse CaregiversU01AG013265 · NIA · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 1996 to 2003
$1.9M
TREATMENT OF DISTRESS IN HISPANIC AND ANGLO CAREGIVERSU01AG013289 · NIA · STANFORD UNIVERSITY · PI GALLAGHER-THOMPSON, DOLORES ELIZABETH · 1995 to 2003
$1.5M
SKILL TRAINING FOR AFRICAN AMERICAN AND WHITE CAREGIVERSU01NR004261 · NINR · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI BURGIO, LOUIS DONALD · 1995 to 2003
$1.4M
PROVIDERS AND ALZHEIMERS CAREGIVERS TOGETHER (PACT)U01AG013313 · NIA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI BURNS, ROBERT · 1995 to 2003
$1.4M
Tailored Activity to Improve Affect in Dementia at HomeR21MH069425 · NIMH · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2004 to 2006
$584k
NIA NIH HHS R01 AG022254NIA NIH HHS R01 AG041781NIA NIH HHS R01 AG049692NIA NIH HHS T32 AG000247NIA NIH HHS U01 AG013265NIA NIH HHS U01 AG013289NIA NIH HHS U01 AG013305NIA NIH HHS U01 AG013313NIMH NIH HHS R21 MH069425NINR NIH HHS U01 NR004261
6 · The paper itself

Abstract

objectivesTo determine whether caregiver relationship and race modify associations between physical functioning of persons with dementia (PWD) and their caregiver's burden and general depressive symptoms.

methodWe pooled data from four behavioral intervention trials (N = 1,211). Using latent growth modeling, we evaluated associations of PWD physical functioning with the level and rate of change in caregiver burden and caregivers' general depressive symptoms and stratified these associations by caregiver relationship and race.

resultsPWD were, on average, 81 years old (68% female) with mean follow-up of 0.5 years. More baseline PWD physical impairment was associated with less worsening in caregiver burden over time (β = -0.23, 95% CI: -0.29, -0.14), but this relationship was not modified by caregiver characteristics. More impaired baseline PWD physical functioning was not associated with changes in depressive symptoms (β = -0.08, 95% CI: -0.17, 0.00), but was associated with less worsening in depressive symptoms among spousal (β = -0.08, 95% CI: -0.17, 0.00) and non-white (β = -0.08, 95% CI: -0.17, 0.00) caregivers.

conclusionsDementia caregivers may experience reduced caregiver-related burden because of adjustment to PWD functional status, while spousal and non-white caregivers may experience less depressive symptoms resultant of adjustment to functional status.

Indexed as

Clinical Trials as TopicCost of IllnessAdultAgedAged, 80 and overCaregiversDementiaDepressionFamilyFemaleHumansMaleMiddle Agedcaregiver burdendementiadepressionharmonizationPhysical functioning

Identifiers

PMID29469590
PMCPMC6172154
OpenAlexW2791260631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.