Evidence map›Paper›PMID 29468731›Full record

ReviewActa paediatrica (Oslo, Norway : 1992)2018

Nutritional influences on brain development.

Michael K Georgieff, Sara E Ramel, Sarah E Cusick

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta paediatrica (Oslo, Norway : 1992), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  8. The Escape from Malnutrition of Chilean Boys and Girls: Height-for-Age Z Scores in Late XIX and XX Centuries.International journal of environmental research and public health · 2021
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91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael K GeorgieffDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Sara E RamelDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Sarah E CusickDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.

Funding

NEWBORN IRON DEFICIENCYR01HD029421 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI GEORGIEFF, MICHAEL K. · 2000 to 2015
$4.4M
Acute vs. Delayed Iron: Effect on Red Cell Iron Incorporation in Severe MalariaR03HD074262 · NICHD · UNIVERSITY OF MINNESOTA · PI CUSICK, SARAH · 2012 to 2013
$129k
NEWBORN IRON DEFICIENCY IN INFANTS OF DIABETIC MOTHERSR29HD029421 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI GEORGIEFF, MICHAEL K. · 1995 to 1999
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NICHD NIH HHS R01 HD029421NICHD NIH HHS R03 HD074262NICHD NIH HHS R29 HD029421
6 · The paper itself

Abstract

There is increasing evidence from preclinical and human studies that nutrition in the late foetal and early neonatal period has a significant impact on neurodevelopment across the lifespan. Certain nutrients have particularly large effects in this time period, and their deficits cause greater long-term risk. The mechanisms by which nutrients influence early brain growth and the sensitive periods for when certain nutrients should be provided are being elucidated. Assessments of nutritional status that index brain growth and predict long-term development are important to assess the efficacy of early life nutritional therapies.

conclusionOptimizing nutrition during foetal and early postnatal life is a golden opportunity to impact neurodevelopment and brain function across the lifespan.

Indexed as

Nutritional RequirementsAge FactorsBrainChild DevelopmentChild, PreschoolFemaleFetal DevelopmentFollow-Up StudiesHumansInfantInfant, NewbornMaleNeurodevelopmental DisordersNutrientsPregnancyRisk AssessmentNutrientsBrainDevelopmentFoetusNeonateNutrition

Identifiers

PMID29468731
PMCPMC6045434

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.