Evidence map›Paper›PMID 29468519›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2018

Effect of Pressure Support Ventilation on Carboxyhemoglobin Toxicokinetic after Acute Carbon Monoxide Intoxication: a Swine Model.

N Delvau, A Penaloza, G Liistro, F Thys, I K Delattre, Philippe Hantson, P Gianello, P M Roy

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

N DelvauDepartment of Emergency Medicine, Cliniques universitaires Saint-Luc, Université Catholique de Louvain, 1200, Brussels, Belgium.
A PenalozaDepartment of Emergency Medicine, Cliniques universitaires Saint-Luc, Université Catholique de Louvain, 1200, Brussels, Belgium.
G LiistroDepartment of Pneumology, Cliniques universitaires Saint-Luc, Université Catholique de Louvain, 1200, Brussels, Belgium.
F ThysEmergency Department, Grand Hôpital de Charleroi, 6000, Charleroi, Belgium.
I K DelattreLouvain center for Toxicology and Applied Pharmacology (LTAP), Université Catholique de Louvain, 1200, Brussels, Belgium.
Philippe HantsonLouvain center for Toxicology and Applied Pharmacology (LTAP), Université Catholique de Louvain, 1200, Brussels, Belgium. philippe.hantson@uclouvain.be.
P GianelloDepartment of Health Sciences, Institute for Experimental and Clinical, Experimental Surgery and Transplantation (CHEX), Université Catholique de Louvain, 1200, Brussels, Belgium.
P M RoyDepartment of Emergency Medicine, Centre Hospitalier Universitaire, 49033, Angers Cedex 01, France.
UCLouvain · BECliniques Universitaires Saint-Luc · BECentre Hospitalier Universitaire d'Angers · FRGrand Charleroi Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn an experimental study on carbon monoxide (CO) exposure in swine, we aimed to compare the influence of oxygen therapy using a non-rebreathing mask (NRM) to continuous positive airway pressure (CPAP) and two pressure support ventilation (PSV) devices on the decrease of the terminal elimination half-life of carboxyhemoglobin (COHb t

methodsEight spontaneously breathing pigs were sedated by propofol and exposed to 940 ppm CO several times (n = 25) to obtain COHb levels of 30%. CPAPb (high flow open system, CPAP Boussignac® [7.5 cmH

resultsMedian FiO

conclusionIn conclusion, in our study on CO intoxication in swine, the use of the closed PSV-Leg system led to the shortest COHb t

Indexed as

AnimalsCarbon Monoxide PoisoningCarboxyhemoglobinContinuous Positive Airway PressureHalf-LifeMaleOxygenPilot ProjectsProspective StudiesRespiration, ArtificialSwineToxicokineticsTreatment OutcomeCarboxyhemoglobinOxygenCarbon monoxideCarboxyhemoglobin (COHb)Continuous positive airway pressure (CPAP)Oxygen therapyPositive pressure ventilationSwineToxicokinetic

Identifiers

PMID29468519
PMCPMC5962466
OpenAlexW2793109999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.