SynthesisNeuropsychology review2018
A Systematic Review of Cognition in Chiari I Malformation.
Synthesis in Neuropsychology review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Cognition in Chiari Malformation Type I: an Update of a Systematic Review.Neuropsychology review · 2024Pooled it
- Chiari I malformation.Nature reviews. Disease primers · 2026Review
- The CCAS-Scale in Chiari Malformation Type I: A Cerebellar-Focused Cognitive Assessment with Clinical Utility.Cerebellum (London, England) · 2026Article
- Chiari I Malformation as a Human Disease Model of Cerebellar Cognitive-Affective Dysfunction.Cerebellum (London, England) · 2026Review
- High-Resolution Diffusion Tensor Imaging of the Cerebellum and Brainstem in Chiari Malformation Type I: Association with Function and Pain.Cerebellum (London, England) · 2026Article
- Episodic Memory, Chiari I Malformation, Personality and Coping: The Role of Chronic Pain.Behavioral sciences (Basel, Switzerland) · 2025Review
- Mapping the neurocognitive landscape of pediatric Chiari malformation type I: a scoping review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Impact of chronic pain and depressive symptoms on the quality of life of adults with Chiari Malformation type I: A comparative study.Intractable & rare diseases research · 2024Article
- Relationship of Morphometrics and Symptom Severity in Female Type I Chiari Malformation Patients with Biological Resilience.Cerebellum (London, England) · 2024Article
- Chiari I malformation: management evolution and technical innovation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Association between resistance to cerebrospinal fluid flow and cardiac-induced brain tissue motion for Chiari malformation type I.Neuroradiology · 2023Article
- Chiari Type 1 Malformation and Syringomyelia in Children: Classification and Treatment Options.Advances and technical standards in neurosurgery · 2023Review
- Article
- Chiari Malformation Type 1 and Syringomyelia: Why Do Patients Claim for International Guidelines? Commentary on the 2021 Chiari and Syringomyelia Consensus Document.Acta neurochirurgica. Supplement · 2023Article
- Adult Age Differences in Self-Reported Pain and Anterior CSF Space in Chiari Malformation.Cerebellum (London, England) · 2022Article
- Diagnosis and treatment of Chiari malformation type 1 in children: the International Consensus Document.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- A Clinical Study on the Treatment of Recurrent Chiari (Type I) Malformation with Syringomyelia Based on the Dynamics of Cerebrospinal Fluid.BioMed research international · 2022Article
- Influence of Pain on Cognitive Dysfunction and Emotion Dysregulation in Chiari Malformation Type I.Advances in experimental medicine and biology · 2022Review
- Surgical Outcomes of C1-2 Posterior Stabilization in Patients With Chiari Malformation Type 1.Global spine journal · 2022Article
- Cognitive and Psychological Functioning in Chiari Malformation Type I Before and After Surgical Decompression - A Prospective Cohort Study.Neurosurgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Displacement of the cerebellar tonsils in Chiari type I malformation (CMI) can affect functions controlled by the cerebellum and brainstem. While playing an integral role in the control of movement, the cerebellum also has widespread cortical connections, influencing a range of cognitive process. A systematic literature review was conducted to examine the relationship between cognition and CMI, assessing evidence for general or domain-specific cognitive change. The search protocol examined the AMED, CINAHL, Cochrane Library, EMBASE, MEDLINE, PsycINFO, and Scopus databases. Articles meeting the following criteria were included in this review (i) examined children or adults with a clinically defined diagnosis of CMI, (ii) assessed cognitive function with a prospective examination, (iii) included at least one standardized instrument designed to measure general or specific domains of cognitive function, and (iv) were published in English in a peer-reviewed journal. Twelve articles were identified, including 783 cases aged 3 months to 64 years. General cognition, processing speed, and learning and memory appeared less affected, while language deficits appeared to diminish with age. Executive dysfunction was the most commonly reported cognitive impairment, while attention and working memory, and visuospatial and perceptual skills also appeared vulnerable. Numerous methodological limitations were identified that should be considered in interpreting the impact of CMI and planning future investigations. Overall, there is currently insufficient evidence to describe a valid and reliable profile of cognitive impairment in CMI. Further research is required to confirm these preliminary psychometric results and integrate them with pathophysiological models.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.