Evidence map›Paper›PMID 29468473›Full record

ArticleHeart and vessels2018

Clinical aspects of myocardial fibrosis in adults with Ebstein's anomaly.

Aleksandra Ciepłucha, Olga Trojnarska, Anna Kociemba, Magdalena Łanocha, Mikolaj Barczynski, Szymon Rozmiarek, Lucyna Kramer, Malgorzata Pyda

Open access · bronzeAbstract read
In one paragraph

Article in Heart and vessels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Clinical and Imaging Predictors of Poor Prognosis in Ebstein Anomaly.CJC pediatric and congenital heart disease · 2025
    Review
  2. Article
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  13. Ebstein's Anomaly.Methodist DeBakey cardiovascular journal
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aleksandra CiepłuchaDepartment of Cardiology, University of Medical Sciences, ½ Dluga Street, 61-848, Poznan, Poland. ola.cieplucha@gmail.com.ORCID http://orcid.org/0000-0001-7455-0839
Olga TrojnarskaDepartment of Cardiology, University of Medical Sciences, ½ Dluga Street, 61-848, Poznan, Poland.
Anna KociembaCardiac Magnetic Resonance Unit, University of Medical Sciences, Poznan, Poland.
Magdalena ŁanochaDepartment of Cardiology, University of Medical Sciences, ½ Dluga Street, 61-848, Poznan, Poland.
Mikolaj BarczynskiDepartment of Cardiology, University of Medical Sciences, ½ Dluga Street, 61-848, Poznan, Poland.
Szymon RozmiarekCardiac Magnetic Resonance Unit, University of Medical Sciences, Poznan, Poland.
Lucyna KramerDepartment of Computer Sciences and Biostatistics, University of Medical Sciences, Poznan, Poland.
Malgorzata PydaDepartment of Cardiology, University of Medical Sciences, ½ Dluga Street, 61-848, Poznan, Poland.
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure and arrhythmia are common complications in adults with Ebstein's anomaly. They may result not only from hemodynamic alterations, but also from myocardial fibrosis. Late gadolinium enhancement (LGE) by CMR enables the evaluation of myocardial fibrosis. The aim of the study was to asses the presence of LGE and its relation to clinical outcome. We studied a group of 37 unoperated adults aged 43.0 ± 14.4 years with Ebstein's anomaly from the congenital heart disease outpatient clinic. Study protocol included: cardiopulmonary test, assessment of supraventricular arrhythmia (SVA), and CMR with evaluation of cardiac chambers' morphology and function, and presence of LGE. Variables following normal distribution were shown as mean ± SD if otherwise median (range) was applied. Fibrosis was found in 18 patients (48.6%) and was distributed as follows: 12 patients (32.4%) in the right atrium, 12 (32.4%) in the atrialized right ventricle, and 2 (5.4%) in the functional right ventricle. In patients with fibrosis, the tricuspid regurgitation fraction was bigger (48.3 ± 19.7 vs. 36.1 ± 22.6%, p = 0.048) and SVA was more frequent [12 (66.7%) vs. 6 (31.6%), p = 0.046] when compared to patients without fibrosis. However, exercise capacity did not differ between patients with and without LGE (peak VO

Indexed as

AdolescentAdultAgedCardiomyopathiesEbstein AnomalyExercise ToleranceFemaleFibrosisHeart FailureHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardiumPrognosisCongenital heart diseaseEbstein’s anomalyExercise capacityLate gadolinium enhancementMyocardial fibrosis

Identifiers

PMID29468473
PMCPMC6096744
OpenAlexW2790074029

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.