Evidence map›Paper›PMID 29468311›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Lena Thomas, Steffi Kantz, Arthur Hung, Debra Monaco, Florian C Gaertner, Markus Essler, Holger Strunk, Wolfram Laub, Ralph A Bundschuh

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Interobserver variability in dominant intraprostatic lesion delineation usingReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
    Article
  4. Molecular Imaging in Photon Radiotherapy.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  5. Biomarkers in Localized Prostate Cancer: From Diagnosis to Treatment.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Combination ofCancer management and research · 2021
    Article
  15. Recent advances of PET imaging in clinical radiation oncology.Radiation oncology (London, England) · 2020
    Review
  16. Comparison of Manual and Semi-Automatic [Frontiers in oncology · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lena ThomasKlinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany. lenathomas.klinik@gmail.com.
Steffi KantzLMU Munich, Department of Radiation Oncology, Munich, Germany.
Arthur HungDepartment of Radiation Medicine, Oregon Health and Science University, Portland, OR, USA.
Debra MonacoDepartment of Radiation Medicine, Oregon Health and Science University, Portland, OR, USA.
Florian C GaertnerKlinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Markus EsslerKlinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Holger StrunkRadiologische Klinik, Universitätsklinikum Bonn, Bonn, Germany.
Wolfram LaubDepartment of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ralph A BundschuhKlinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.ORCID 0000-0001-7291-9372

Funding

Deutsche Forschungsgemeinschaft BU 3395/1-1
6 · The paper itself

Abstract

purposeThe purpose of our study was to show the feasibility and potential benefits of using

methodsTwenty-one prostate cancer patients (70 years average) without previous local therapy received

resultsComparing the conventional plans to the plans with integrated boost and plans just treating the PET-positive tumor volume, we found that TCP increased to (95.2 ± 0.5%) for an integrated boost with 75.6 Gy, (98.1 ± 0.3%) for an integrated boost with 80 Gy, (94.7 ± 0.8%) for treatment of PET-positive volume with 75 Gy, and to (99.4 ± 0.1%) for treating PET-positive volume with 95 Gy (all p < 0.0001). For the integrated boost with 80 Gy, a significant increase of the median NTCP of the rectum was found, for all other plans no statistical significant increase in the NTCP neither of the rectum nor the bladder was found.

conclusionsOur study demonstrates that the use of

Indexed as

Positron Emission Tomography Computed TomographyRadiotherapy, Intensity-ModulatedAgedAged, 80 and overGermanyHumansMaleMiddle AgedProstatic NeoplasmsRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesTomography, X-Ray ComputedPET/CTProstate cancerPSMARadiation treatment planning

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.