Evidence map›Paper›PMID 29468122›Full record

ArticleMetabolic engineering communications2016

A genetic screen for increasing metabolic flux in the isoprenoid pathway of

M Wadhwa, A K Bachhawat

Open access · goldAbstract read
In one paragraph

Article in Metabolic engineering communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M WadhwaDepartment of Biological Sciences, Indian Institute of Science Education and Research, Mohali, S.A.S Nagar, Punjab 140306, India.
A K BachhawatDepartment of Biological Sciences, Indian Institute of Science Education and Research, Mohali, S.A.S Nagar, Punjab 140306, India.
Indian Institute of Science Education and Research Mohali · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A genetic screen to identify mutants that can increase flux in the isoprenoid pathway of yeast has been lacking. We describe a carotenoid-based visual screen built with the core carotenogenic enzymes from the red yeast

Indexed as

CarotenoidsC, CYC promoterCRTI, phytoene dehydrogenaseGGPPS, Geranylgeranyl diphosphate synthaseIsoprenoidsMetabolic engineeringPSY1, phytoene synthaseRhodosporidium toruloidesSPT15T, TEF promoterα-Farnesene

Identifiers

PMID29468122
PMCPMC5779727
OpenAlexW2396782511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.