Evidence map›Paper›PMID 29468114›Full record

ArticleMetabolic engineering communications2016

Mitochondrial targeting increases specific activity of a heterologous valine assimilation pathway in

Kevin V Solomon, Elisa Ovadia, Fujio Yu, Wataru Mizunashi, Michelle A O'Malley

Open access · goldAbstract read
In one paragraph

Article in Metabolic engineering communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kevin V SolomonDepartment of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA 93106, United States.
Elisa OvadiaDepartment of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA 93106, United States.
Fujio YuScience and Technology Research Center, Inc., Mitsubishi Rayon Group, Yokohama, Kanagawa 227-8502, Japan.
Wataru MizunashiScience and Technology Research Center, Inc., Mitsubishi Rayon Group, Yokohama, Kanagawa 227-8502, Japan.
Michelle A O'MalleyDepartment of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA 93106, United States.
University of California, Santa Barbara · USMitsubishi Chemical Group Science and Technology Research Center (Japan) · JP

Funding

Spectral Laser Scanning Biological MicroscopeS10OD010610 · OD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI RAVEN, MARY A · 2012 to 2012
$429k
NIH HHS S10 OD010610
6 · The paper itself

Abstract

Bio-based isobutantol is a sustainable 'drop in' substitute for petroleum-based fuels. However, well-studied production routes, such as the Ehrlich pathway, have yet to be commercialized despite more than a century of research. The more versatile bacterial valine catabolism may be a competitive alternate route producing not only an isobutanol precursor but several carboxylic acids with applications as biomonomers, and building blocks for other advanced biofuels. Here, we transfer the first two committed steps of the pathway from pathogenic

Indexed as

DehydrogenaseIsobutanolMetabolic engineeringMitochondriaPseudomonasSaccharomyces cerevisiae

Identifiers

PMID29468114
PMCPMC5779707
OpenAlexW2302180229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.