Evidence map›Paper›PMID 29468085›Full record

ArticlePilot and feasibility studies2018

Feasibility of a combined aerobic and cognitive training intervention on cognitive function in cancer survivors: a pilot investigation.

Brent M Peterson, Cynthia Johnson, Kaylene R Case, Daniel Y K Shackelford, Jessica M Brown, Trent L Lalonde, Reid Hayward

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  15. Breast Cancer, Alzheimer's Disease, andJournal of Alzheimer's disease reports · 2021
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  16. Advances and future directions in the use of mobile health in supportive cancer care: proceedings of the 2019 MASCC Annual Meeting symposium.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Brent M Peterson1Department of Kinesiology and Health Science, Biola University, 13800 Biola Ave., La Mirada, CA 90639 USA.
Cynthia Johnson4School of Psychological Sciences, University of Northern Colorado, Greeley, CO USA.
Kaylene R Case4School of Psychological Sciences, University of Northern Colorado, Greeley, CO USA.
Daniel Y K Shackelford2Department of Exercise Science, Carroll University, 100 N. East Ave., Waukesha, WI 53186 USA.
Jessica M Brown2Department of Exercise Science, Carroll University, 100 N. East Ave., Waukesha, WI 53186 USA.
Trent L Lalonde5Department of Applied Statistics and Research Methods, University of Northern Colorado, Greeley, CO USA.
Reid Hayward3School of Sport and Exercise Science, University of Northern Colorado Cancer Rehabilitation Institute, University of Northern Colorado, 501 W. 20th St., Greeley, CO 80639 USA.
University of Northern Colorado · USBiola University · USCarroll University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer-related cognitive impairment (CRCI) may negatively affect upwards of 75% of cancer patients. Exercise and cognitive training, independently, may increase functional capacity and aspects of cognitive function. Yet, combined training protocols have not been evaluated in cancer survivor populations. Therefore, the aim of this study was to explore the feasibility of a quasi-randomized, controlled, exploratory, repeated-measures aerobic and cognitive training intervention on cognitive function in participants undergoing treatment for cancer (

methodsPre- and post-physical and cognitive assessments were administered. A 36-session (approximately 12 weeks) computer-based cognitive (COG), aerobic (AER), cognitive and aerobic (AER + COG), and flexibility (CON) training intervention was completed. Dependent measures

resultsWithin-group measures revealed that the AER logical memory scores (pre- to post mean difference [2.3], 95.0% CI [0.9, 3.7], percentage change [32.7%]), delayed recall scores (pre- to post mean difference [2.1], 95.0% CI [0.3, 3.9], percentage change [27.2%]), block design scores (pre- to post mean difference [1.7], 95.0% CI [0.2, 3.2], percentage change [19.0%]), and letter-number sequencing scores (pre- to post mean difference [1.0], 95.0% CI [0.2, 1.8], percentage change [12.3%]) all increased. Aspects of verbal fluidity scores increased in the CON group. However, all cognitive scores (AER + COG and COG groups) failed to increase.

conclusionsAerobic training for CRCI may positively impact cognitive function. Individually, these methods may appropriately address CRCI, but combined training of this nature may be too demanding for patients undergoing treatment for cancer. However, larger randomized trials are needed to substantiate this protocol in large-scale cancer rehabilitation centers.

Indexed as

CancerCancer-related cognitive impairmentChemotherapy-related cognitive impairmentCognitive functionExercise

Identifiers

PMID29468085
PMCPMC5816373
OpenAlexW2803484730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.