Evidence map›Paper›PMID 29468066›Full record

ArticleSAGE open medicine2018

Evaluation of lipid profiles and hematological parameters in hypertensive patients: Laboratory-based cross-sectional study.

Alemu Gebrie, Natesan Gnanasekaran, Menakath Menon, Mekonnen Sisay, Abriham Zegeye

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Article
  7. Lipoprotein(a): Just an Innocent Bystander in Arterial Hypertension?International journal of molecular sciences · 2023
    Review
  8. Relationship Between Lipid Profile and Sensorineural Hearing Loss: An Institution Based Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
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  17. A Biochemical Analysis of Patients with COVID-19 Infection.Biochemistry research international · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alemu GebrieMedical Biochemistry, Department of Biomedical Sciences, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Natesan GnanasekaranMedical Biochemistry, Department of Biochemistry, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Menakath MenonMedical Biochemistry, Department of Biochemistry, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Mekonnen SisayDepartment of Pharmacology and Toxicology, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.ORCID https://orcid.org/0000-0001-6611-1174
Abriham ZegeyeMedical Physiology, Department of Biomedical Sciences, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Addis Ababa University · ETDebre Markos University · ETHaramaya University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension and dyslipidemia are the two coexisting and synergizing major risk factors for cardiovascular diseases. The cellular constituents of blood affect the volume and viscosity of blood, thus playing a key role in regulating blood pressure. Overweight and obesity are key determinants of adverse metabolic changes including an increase in blood pressure. The aim of this study was to evaluate lipid profiles and hematological parameters in hypertensive patients at Debre Markos Referral Hospital, Northwest Ethiopia.

methodsLaboratory-based cross-sectional study was conducted in 100 eligible hypertensive patients at the hospital. The required amount of blood was withdrawn from the patients by healthcare professionals for immediate automated laboratory analyses. Data were collected on socio-demographic factors, anthropometric measurements, blood pressure, lipid profiles, and hematological parameters.

resultThe mean serum levels of triglyceride, total cholesterol, and low-density lipoprotein were significantly higher than their respective cut-off values in the hypertensive patients. Besides, 54%, 52%, 35%, and 11% of the hypertensive patients had abnormal low-density lipoprotein, total cholesterol, triglyceride, and high-density lipoprotein levels, respectively. Higher levels of low-density lipoprotein, hemoglobin, and red blood cell count were observed in the hypertensive patients whose blood pressure had been poorly controlled than the controlled ones (

conclusionHypertensive patients had a high prevalence of lipid profile abnormalities and poorly controlled blood pressure which synergize in accelerating other cardiovascular diseases. Some hematological parameters such as red blood cell count are also increased as do the severity of hypertension.

Indexed as

anthropometric indicatorshematological parametersHypertensionlipid profiles

Identifiers

PMID29468066
PMCPMC5813853
OpenAlexW2790043083

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.