Evidence map›Paper›PMID 29467962›Full record

ReviewOncotarget2018

Inflammatory responses and inflammation-associated diseases in organs.

Linlin Chen, Huidan Deng, Hengmin Cui, Jing Fang, Zhicai Zuo, Junliang Deng, Yinglun Li, Xun Wang, Ling Zhao

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05798182 (Ultrasound in the Intensive Care Unit and Measurable Indicators of Systemic Inflammation), which is not on this map. Cited by 2,333 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,333citing papers in PubMed, 6 pooled it
77.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05798182 completednot on this mapstarted 2020, after this paper: background citation

Ultrasound in the Intensive Care Unit and Measurable Indicators of Systemic Inflammation

TypeobservationalSponsorOsijek University HospitalRan2020 to 2021Enrolled61ConditionsInflammation Process, Endothelial Dysfunction, Vasomotor Arterial Disorder, Vascular DilationArmsUltrasound measurement
3 · Its place in the literature

Who cites it

2,333 citing papers in PubMed, 6 syntheses or guidelines pooled it, 4,861 citations in OpenAlex.

  1. Pooled it
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  12. Pathological and morphometric characterization of intestinal lesions associated with natural infection byInternational journal for parasitology. Parasites and wildlife · 2026
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  15. Journal of enzyme inhibition and medicinal chemistry · 2026
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2,273 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Linlin Chen *College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Huidan Deng *College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Hengmin CuiCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Jing FangCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Zhicai ZuoCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Junliang DengCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Yinglun LiCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Xun WangCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Ling ZhaoCollege of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a biological response of the immune system that can be triggered by a variety of factors, including pathogens, damaged cells and toxic compounds. These factors may induce acute and/or chronic inflammatory responses in the heart, pancreas, liver, kidney, lung, brain, intestinal tract and reproductive system, potentially leading to tissue damage or disease. Both infectious and non-infectious agents and cell damage activate inflammatory cells and trigger inflammatory signaling pathways, most commonly the NF-κB, MAPK, and JAK-STAT pathways. Here, we review inflammatory responses within organs, focusing on the etiology of inflammation, inflammatory response mechanisms, resolution of inflammation, and organ-specific inflammatory responses.

Indexed as

chemokinescytokinesinflammationinflammatory signaling pathwaysorgan diseases

Identifiers

PMID29467962
PMCPMC5805548
OpenAlexW2771472591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.