Evidence map›Paper›PMID 29467799›Full record

ArticleNutrition & metabolism2018

Exposure to maternal cafeteria diets during the suckling period has greater effects on fat deposition and Sterol Regulatory Element Binding Protein-1c (SREBP-1c) gene expression in rodent offspring compared to exposure before birth.

M A Vithayathil, J R Gugusheff, Z Y Ong, S C Langley-Evans, R A Gibson, B S Muhlhausler

Open access · goldAbstract read
In one paragraph

Article in Nutrition & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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  7. Early life programming of health and disease: The long-term consequences of obesity in pregnancy.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

M A Vithayathil1FOODplus Research Centre, Department of Wine and Food Sciences, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, South Australia 5064 Australia.
J R Gugusheff1FOODplus Research Centre, Department of Wine and Food Sciences, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, South Australia 5064 Australia.
Z Y Ong1FOODplus Research Centre, Department of Wine and Food Sciences, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, South Australia 5064 Australia.
S C Langley-Evans4School of Biosciences, University of Nottingham, Sutton Bonington, Loughborough, LE12 5RD UK.
R A Gibson1FOODplus Research Centre, Department of Wine and Food Sciences, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, South Australia 5064 Australia.
B S Muhlhausler1FOODplus Research Centre, Department of Wine and Food Sciences, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, South Australia 5064 Australia.
University of Adelaide · AUSouth Australian Health and Medical Research Institute · AUUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the adverse metabolic effects of exposure to obesogenic diets during both the prenatal and early postnatal period are well established, the relative impact of exposure during these separate developmental windows remains unclear. This study aimed to assess the relative contribution of exposure to a maternal cafeteria diet during pregnancy and lactation on body weight, fat mass and expression of lipogenic and adipokine genes in the offspring.

methodsWistar rats were fed either a control chow (Control,

resultsOffspring suckled by CAF dams had a lower body weight (

conclusionsThe findings from this study point to the critical role of the suckling period for deposition of adipose tissue in rodents, and the potential role of altered adipocyte gene expression in mediating these effects.

Indexed as

Cafeteria dietFat depositionFetal programmingLactationMaternal nutritionPregnancy

Identifiers

PMID29467799
PMCPMC5815184
OpenAlexW2789708633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.