Evidence map›Paper›PMID 29467762›Full record

ArticleFrontiers in immunology2018

Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three

Stephanie R Harrison, Thomas Scambler, Lylia Oubussad, Chi Wong, Miriam Wittmann, Michael F McDermott, Sinisa Savic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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  9. [Clinical symptoms of autoinflammatory diseases].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephanie R HarrisonLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
Thomas ScamblerLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
Lylia OubussadLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
Chi WongLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
Miriam WittmannLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
Michael F McDermottLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
Sinisa SavicLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Leeds, United Kingdom.
NIHR Leeds Musculoskeletal Biomedical Research Unit · GBSt James's University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor (TNF)-receptor-associated periodic fever syndrome (TRAPS) is a rare monogenic autoinflammatory disorder characterized by mutations in the

Indexed as

BiopsyCytokinesDermisDown-RegulationEndoribonucleasesEnzyme InhibitorsFibroblastsHereditary Autoinflammatory DiseasesHumansInterleukin-1betaLipopolysaccharidesMicroRNAsMutationNerve Tissue ProteinsProtein Serine-Threonine KinasesSignal TransductionBABAM2 protein, humanCytokinesEndoribonucleasesEnzyme InhibitorsERN1 protein, humanInterleukin-1betaLipopolysaccharidesMicroRNAsMIRN146 microRNA, humanMIRN155 microRNA, humanNerve Tissue ProteinsProtein Serine-Threonine KinasesThapsigarginTumor Necrosis Factor-alphaautoinflammationinisitol-requiring enzyme 1lipopolysaccharidemicroRNA-146amicroRNA-155toll-like receptor 4tumor necrosis factor-receptor-associated periodic syndromeunfolded protein response

Identifiers

PMID29467762
PMCPMC5808292
OpenAlexW2787906517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.