Evidence map›Paper›PMID 29467757›Full record

ArticleFrontiers in immunology2018

Genetic Regulation of Guanylate-Binding Proteins 2b and 5 during Leishmaniasis in Mice.

Yahya Sohrabi, Valeryia Volkova, Tatyana Kobets, Helena Havelková, Imtissal Krayem, Martina Slapničková, Peter Demant, Marie Lipoldová

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Human GBP1 Is Involved in the Repair of Damaged Phagosomes/Endolysosomes.International journal of molecular sciences · 2023
    Article
  10. Functionally distinct regions of the locusFrontiers in immunology · 2023
    Article
  11. Role of interferon-induced GTPases in leishmaniasis.PLoS neglected tropical diseases · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yahya SohrabiLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Valeryia VolkovaLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Tatyana KobetsLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Helena HavelkováLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Imtissal KrayemLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Martina SlapničkováLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Peter DemantDepartment of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY, United States.
Marie LipoldováLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.
Czech Academy of Sciences, Institute of Molecular Genetics · CZRoswell Park Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-induced GTPases [guanylate-binding proteins (GBPs)] play an important role in inflammasome activation and mediate innate resistance to many intracellular pathogens, but little is known about their role in leishmaniasis. We therefore studied expression of

Indexed as

AnimalsFemaleGene Expression RegulationGTP-Binding ProteinsLeishmaniasis, CutaneousLiverLymph NodesMice, Inbred BALB CMice, Inbred C57BLSkinSpecies SpecificitySpleenGbp2b protein, mouseGbp5 protein, mouseGTP-Binding Proteinsa hidden inflammationgenetic controlguanylate-binding proteinsLeishmania majorrecombinant congenic strains

Identifiers

PMID29467757
PMCPMC5808352
OpenAlexW2790674896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.