Evidence map›Paper›PMID 29467649›Full record

ArticleFrontiers in pharmacology2018

Tolerance and Tachyphylaxis to Head Twitches Induced by the 5-HT2A Agonist 25CN-NBOH in Mice.

Tobias Buchborn, Taylor Lyons, Thomas Knöpfel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Deconstruction of lysergic acid diethylamide.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Sex-specific role of the 5-HTNature communications · 2025
    Article
  6. The Selective Serotonin 5‑HTACS pharmacology & translational science · 2025
    Article
  7. Article
  8. Article
  9. Psychedelic enhancement of flexible learning weeks after a single dose.bioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Altered Serotonin 2A (5-HTFrontiers in pharmacology · 2022
    Article
  18. Article
  19. DARK Classics in Chemical Neuroscience: NBOMes.ACS chemical neuroscience · 2020
    Review
  20. The Chronic Treatment With 5-HTNeurochemical research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tobias BuchbornLaboratory for Neuronal Circuit Dynamics, Department of Medicine, Imperial College London, London, United Kingdom.
Taylor LyonsLaboratory for Neuronal Circuit Dynamics, Department of Medicine, Imperial College London, London, United Kingdom.
Thomas KnöpfelLaboratory for Neuronal Circuit Dynamics, Department of Medicine, Imperial College London, London, United Kingdom.
Imperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The serotonin (5-HT) 2A receptor is the primary molecular target of serotonergic hallucinogens, which trigger large-scale perturbations of the cortex. Our understanding of how 5-HT

Indexed as

25CN-NBOH5-HT2A receptor5-HT2C receptorhead twitch responselocomotionserotonergic hallucinogentachyphylaxistolerance

Identifiers

PMID29467649
PMCPMC5808243
OpenAlexW2794014176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.