Evidence map›Paper›PMID 29467648›Full record

ReviewFrontiers in aging neuroscience2018

Dissecting Endoplasmic Reticulum Unfolded Protein Response (UPR

Safikur Rahman, Ayyagari Archana, Arif Tasleem Jan, Rinki Minakshi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Deciphering the Link Between ERFrontiers in aging neuroscience · 2022
    Review
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  8. Review
  9. Review
  10. Article
  11. Review
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  14. Article
  15. The onus of cannabinoids in interrupting the molecular odyssey of breast cancer: A critical perspective on UPRSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Safikur RahmanDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan, South Korea.
Ayyagari ArchanaDepartment of Microbiology, Swami Shraddhanand College, University of Delhi, New Delhi, India.
Arif Tasleem JanSchool of Biosciences and Biotechnology, Baba Ghulam Shah Badshah University, Rajouri, India.
Rinki MinakshiInstitute of Home Economics, University of Delhi, New Delhi, India.
University of Delhi · INBaba Ghulam Shah Badshah University · INYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD), a neurodegenerative disorder, is most common cause of dementia witnessed among aged people. The pathophysiology of AD develops as a consequence of neurofibrillary tangle formation which consists of hyperphosphorylated microtubule associated tau protein and senile plaques of amyloid-β (Aβ) peptide in specific brain regions that result in synaptic loss and neuronal death. The feeble buffering capacity of endoplasmic reticulum (ER) proteostasis in AD is evident through alteration in unfolded protein response (UPR), where UPR markers express invariably in AD patient's brain samples. Aging weakens UPR

Indexed as

agingAlzheimer diseaseendoplasmic reticulum stress (ER)neurodegenerative diseasesUPR (unfolded protein response)

Identifiers

PMID29467648
PMCPMC5808164
OpenAlexW2793528591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.