Evidence map›Paper›PMID 29467644›Full record

ReviewFrontiers in aging neuroscience2018

Use of Peptides for the Management of Alzheimer's Disease: Diagnosis and Inhibition.

Mohammad H Baig, Khurshid Ahmad, Gulam Rabbani, Inho Choi

Abstract readReview
In one paragraph

Review in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
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  11. Article
  12. Anti-Life (Basel, Switzerland) · 2023
    Article
  13. Protein Interactome of Amyloid-β as a Therapeutic Target.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. MIF1 and MIF2 Myostatin Peptide Inhibitors as Potent Muscle Mass Regulators.International journal of molecular sciences · 2022
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad H BaigDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan, South Korea.
Khurshid AhmadDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan, South Korea.
Gulam RabbaniDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan, South Korea.
Inho ChoiDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a form of dementia and the most common progressive neurodegenerative disease (ND). The targeting of amyloid-beta (Aβ) aggregation is one of the most widely used strategies to manage AD, and efforts are being made globally to develop peptide-based compounds for the early diagnosis and treatment of AD. Here, we briefly discuss the use of peptide-based compounds for the early diagnosis and treatment of AD and the use of peptide-based inhibitors targeting various Aβ aggregation checkpoints. In addition, we briefly discuss recent applications of peptide-based inhibitors against various AD targets including amyloid beta, β-site amyloid precursor protein cleaving enzyme 1 (BACE1), Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), tyrosine phosphatase (TP) and potassium channel KV1.3.

Indexed as

Alzheimer’s diseaseamyloid betaBACE-1diagnosisGAPDHinhibitorspeptides

Identifiers

PMID29467644
PMCPMC5808296

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.