Evidence map›Paper›PMID 29467588›Full record

ArticleClinical medicine insights. Circulatory, respiratory and pulmonary medicine2018

Pulmonary Arterial Enlargement is Associated With Acute Chest Pain in Patients Without Obstructive Coronary Artery Disease.

Narasa Madam, Wassim Mosleh, Natdanai Punnanithinont, Andres Carmona-Rubio, Zaid H Said, Umesh C Sharma

Open access · goldAbstract read
In one paragraph

Article in Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Narasa MadamUniversity at Buffalo, The State University of New York, Division of Cardiology, Clinical and Translation Research Center, Buffalo, NY, USA.
Wassim MoslehUniversity at Buffalo, The State University of New York, Division of Cardiology, Clinical and Translation Research Center, Buffalo, NY, USA.
Natdanai PunnanithinontUniversity at Buffalo, The State University of New York, Division of Cardiology, Clinical and Translation Research Center, Buffalo, NY, USA.
Andres Carmona-RubioUniversity at Buffalo, The State University of New York, Division of Cardiology, Clinical and Translation Research Center, Buffalo, NY, USA.
Zaid H SaidUniversity at Buffalo, The State University of New York, Division of Cardiology, Clinical and Translation Research Center, Buffalo, NY, USA.
Umesh C SharmaUniversity at Buffalo, The State University of New York, Division of Cardiology, Clinical and Translation Research Center, Buffalo, NY, USA.
University at Buffalo, State University of New York · US

Funding

Institutional Career DevelopmentKL2TR001413 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2015 to 2024
$4.2M
Galectin-3-Mediated Post-Ischemic Myocardial Dysfunction and its Inhibition by a Novel Peptide N-Acetyl-Seryl-Aspartyl-Lysyl-ProlineK08HL131987 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SHARMA, UMESH C · 2017 to 2021
$987k
NCATS NIH HHS KL2 TR001413NHLBI NIH HHS K08 HL131987
6 · The paper itself

Abstract

backgroundPulmonary hypertension (PH) is an underdiagnosed cause for chest pain in patients without significant coronary artery disease (CAD). Studies showed that enlarged pulmonary arterial (PA) and right ventricular chamber sizes correlate with the severity of PH. Therefore, we studied the association between chest pain, right ventricular dimensions (RVDs), and PA size on coronary coronary tomographic angiography (CCTA).

methodsThe CCTA of 87 patients presenting with chest pain without evidence of obstructive CAD was examined. The PA diameter (PAD), right atrial dimension (RAD), and RVD were measured. A comparative control cohort included 31 patients who presented without cardiopulmonary complaints and underwent thoracic CT. The risk for obstructive sleep apnea (OSA) was assessed using STOP-BANG questionnaires.

resultsPatients with chest pain without obstructive CAD showed markedly dilated right atrial and ventricular chambers compared with standard parameters (right atrium: 48 ± 6.4 mm; right ventricle long axis: 61 ± 9.5 mm). When comparing chest pain vs non-chest pain group, respectively, the mean PAD measured 25.92 ± 0.43 mm vs 22.89 ± 0.38 mm (

conclusionsIn patients presenting with chest pain without obstructive CAD on CCTA, there is a strong association between the presence of chest pain and enlarged PAD. They also represent a high-risk group for OSA.

Indexed as

Chest paincoronary computed tomographic angiographyobstructive sleep apneapulmonary hypertension

Identifiers

PMID29467588
PMCPMC5813846
OpenAlexW2790578082

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.