ArticleScientific reports2018
Transcriptome changes induced by abiotic stresses in Artemisia annua.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 71 citations in OpenAlex.
- RNA-protein complexes as key regulators of plant secondary metabolism: Biophysical interactions and functional significance.Biochemistry and biophysics reports · 2026Review
- Combined drought and high temperature stress enhances saikosaponin biosynthesis in Bupleurum Chinense through multi-level regulatory mechanisms.BMC plant biology · 2025Article
- Unlocking the potential of3 Biotech · 2025Review
- Genomic insights into local adaptation and vulnerability of Quercus longinux to climate change.BMC plant biology · 2024Article
- Variability of plant transcriptomic responses under stress acclimation: a review from high throughput studies.Acta biochimica Polonica · 2024Review
- Transcriptome dynamics inFrontiers in plant science · 2024Article
- Functions of Representative Terpenoids and Their Biosynthesis Mechanisms in Medicinal Plants.Biomolecules · 2023Review
- Genome-wide transcriptional profiling and physiological investigation elucidating the molecular mechanism of multiple abiotic stress response in Stevia rebaudiana Bertoni.Scientific reports · 2023Article
- RNA sequencing in Artemisia annua L explored the genetic and metabolic responses to hardly soluble aluminum phosphate treatment.Functional & integrative genomics · 2023Article
- ABA and SA Participate in the Regulation of Terpenoid Metabolic Flux Induced by Low-Temperature withinLife (Basel, Switzerland) · 2023Article
- The use of chitosan oligosaccharide to improve artemisinin yield in well-watered and drought-stressed plants.Frontiers in plant science · 2023Article
- Comparative transcriptomic analysis provides key genetic resources in clove basil (Frontiers in genetics · 2023Article
- Variation in terpenoids in leaves of Artemisia annua grown under different LED spectra resulting in diverse antimalarial activities against Plasmodium falciparum.BMC plant biology · 2022Article
- Molecular insights into AabZIP1-mediated regulation on artemisinin biosynthesis and drought tolerance inActa pharmaceutica Sinica. B · 2022Article
- Transcriptomic analysis unravels the molecular response ofFrontiers in plant science · 2022Article
- Genome-Wide Analysis of Light-Regulated Alternative Splicing inFrontiers in plant science · 2021Article
- Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin inChinese medicine · 2020Article
- Stress and defense responses in plant secondary metabolites production.Biological research · 2019Review
- Ocimum metabolomics in response to abiotic stresses: Cold, flood, drought and salinity.PloS one · 2019Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artemisia annua is known to be the source of artemisinin worldwide which is an antimalarial compound but is synthesised in very limited amount in the plant. Most research laid emphasis on the methods of enhancing artemisinin but our study has been planned in a way that it may simultaneously address two problems encountered by the plant. Firstly, to know the effect on the artemisinin content in the era of climate change because the secondary metabolites tend to increase under stress. Secondly, to identify some of the stress responsive genes that could help in stress tolerance of the plant under abiotic stress. Hence, the A. annua plants were subjected to four abiotic stresses (salt, cold, drought and water-logging) and it was observed that the artemisinin content increased in all the stress conditions except drought. Next, in order to identify the stress responsive genes, the transcriptome sequencing of the plants under stress was carried out resulting in 89,362 transcripts for control and 81,328, 76,337, 90,470 and 96,493 transcripts for salt, cold, drought, and water logging stresses. This investigation provides new insights for functional studies of genes involved in multiple abiotic stresses and potential candidate genes for multiple stress tolerance in A. annua.
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