Evidence map›Paper›PMID 29467242›Full record

ArticleDevelopment (Cambridge, England)2018

Prothoracicotropic hormone modulates environmental adaptive plasticity through the control of developmental timing.

MaryJane Shimell, Xueyang Pan, Francisco A Martin, Arpan C Ghosh, Pierre Leopold, Michael B O'Connor, Nuria M Romero

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. Article
  3. Science advances · 2025
    Article
  4. NF-κB-mediated developmental delay extends lifespan inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
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  9. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  15. Article
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  17. Article
  18. Review
  19. Endoreplication in themicroPublication biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

MaryJane ShimellDepartment of Genetics Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA oconn033@umn.edu nromero@unice.fr.ORCID 0000-0003-1378-6017
Xueyang PanDepartment of Genetics Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Francisco A MartinUniversity Côte d'Azur, CNRS, Inserm, Institute of Biology Valrose, Parc Valrose, 06108 Nice, France.
Arpan C GhoshDepartment of Genetics Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Pierre LeopoldUniversity Côte d'Azur, CNRS, Inserm, Institute of Biology Valrose, Parc Valrose, 06108 Nice, France.
Michael B O'ConnorDepartment of Genetics Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Nuria M RomeroUniversity Côte d'Azur, CNRS, Inserm, Institute of Biology Valrose, Parc Valrose, 06108 Nice, France oconn033@umn.edu nromero@unice.fr.ORCID 0000-0001-6235-1330
University of Minnesota · USCentre National de la Recherche Scientifique · FR

Funding

Inter-organ signals regulating metabolism, physiology and developmental timingR35GM118029 · NIGMS · UNIVERSITY OF MINNESOTA · PI O'CONNOR, MICHAEL BRENDAN · 2016 to 2025
$3.8M
NIGMS NIH HHS R35 GM118029
6 · The paper itself

Abstract

Adult size and fitness are controlled by a combination of genetics and environmental cues. In

Indexed as

Adaptation, PhysiologicalAnimalsCell PlasticityCuesDrosophilaDrosophila ProteinsEcdysoneEnvironmentImmunohistochemistryInsect HormonesLarvaMetamorphosis, BiologicalMutagenesisReal-Time Polymerase Chain ReactionSignal TransductionDrosophila ProteinsEcdysoneInsect Hormonesprothoracicotropic hormoneDrosophila developmentEcdysoneEnvironmental cuePlasticityPTTH

Identifiers

PMID29467242
PMCPMC5897599
OpenAlexW2788048973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.