Evidence map›Paper›PMID 29467227›Full record

ArticleThe Journal of biological chemistry2018

Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G

Yuqing Shen, John William Sherman, Xuyong Chen, Ruoning Wang

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Article
  5. International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yuqing ShenFrom the Center for Childhood Cancer and Blood Diseases, Hematology/Oncology and BMT, Research Institute at Nationwide Children's Hospital, Ohio State University, Columbus, Ohio 43205 and.
John William ShermanFrom the Center for Childhood Cancer and Blood Diseases, Hematology/Oncology and BMT, Research Institute at Nationwide Children's Hospital, Ohio State University, Columbus, Ohio 43205 and.
Xuyong ChenFrom the Center for Childhood Cancer and Blood Diseases, Hematology/Oncology and BMT, Research Institute at Nationwide Children's Hospital, Ohio State University, Columbus, Ohio 43205 and.
Ruoning WangFrom the Center for Childhood Cancer and Blood Diseases, Hematology/Oncology and BMT, Research Institute at Nationwide Children's Hospital, Ohio State University, Columbus, Ohio 43205 and ruoning.wang@nationwidechildrens.org.
Nationwide Children's Hospital · USSoutheast University · CN

Funding

Metabolic programming in TH17 cell differentiationR01AI114581 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI WANG, RUONING · 2015 to 2025
$3.6M
NIAID NIH HHS R01 AI114581
6 · The paper itself

Abstract

From unicellular to multicellular organisms, cell-cycle progression is tightly coupled to biosynthetic and bioenergetic demands. Accumulating evidence has demonstrated the G

Indexed as

AMP-Activated Protein Kinasescdc25 PhosphatasesCDC2 Protein KinaseCell CycleCell Cycle ProteinsCell Line, TumorCyclin BCyclin-Dependent KinasesG2 PhaseG2 Phase Cell Cycle CheckpointsHeLa CellsHumansMitosisPhosphorylationProtein Serine-Threonine KinasesAMP-Activated Protein KinasesCDC25C protein, humancdc25 PhosphatasesCDC2 Protein KinaseCDK1 protein, humanCell Cycle ProteinsCyclin BCyclin-Dependent KinasesProtein Serine-Threonine KinasesAMP-activated kinase (AMPK)CDC25Ccell cyclemetabolic checkpointmetabolic regulationmitosisprotein phosphorylation

Identifiers

PMID29467227
PMCPMC5892595
OpenAlexW2789194059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.