Evidence map›Paper›PMID 29467214›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2018

Hepatic Transport of 25-Hydroxyvitamin D

Chunying Gao, Michael Z Liao, Lyrialle W Han, Kenneth E Thummel, Qingcheng Mao

Open access · bronzeAbstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Differences in the absorption and metabolism of vitamin DThe Journal of steroid biochemistry and molecular biology · 2025
    Review
  2. Frontiers in endocrinology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Metabolism and pharmacokinetics of vitamin D in patients with cystic fibrosis.The Journal of steroid biochemistry and molecular biology · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Recent advances in the ontogeny of drug disposition.British journal of clinical pharmacology · 2022
    Review
  11. Article
  12. Review
  13. Role of glucuronidated 25-hydroxyvitamin D on colon gene expression in mice.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Article
  14. Article
  15. Drug Transporters in Xenobiotic Disposition and Pharmacokinetic Prediction.Drug metabolism and disposition: the biological fate of chemicals · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chunying GaoDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington.
Michael Z LiaoDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington.
Lyrialle W HanDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington.
Kenneth E ThummelDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington.
Qingcheng MaoDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington qmao@uw.edu.
University of Washington · US

Funding

Hormonal Regulation of Human CYP3AR01GM063666 · NIGMS · UNIVERSITY OF WASHINGTON · PI THUMMEL, KENNETH E. · 2002 to 2017
$5.3M
NIGMS NIH HHS R01 GM063666
6 · The paper itself

Abstract

Vitamin D

Indexed as

25-Hydroxyvitamin D3 1-alpha-HydroxylaseAnimalsCalcitriolCalciumCell LineCHO CellsCholecalciferolCricetulusEnterocytesHEK293 CellsHepatocytesHumansIntestinal MucosaLiverReceptors, CalcitriolSf9 Cells25-Hydroxyvitamin D3 1-alpha-HydroxylaseCalcitriolCalciumCholecalciferoldihydroxy-vitamin D3Receptors, CalcitriolVitamin D

Identifiers

PMID29467214
PMCPMC5896369
OpenAlexW2790887296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.