ArticleThe Journal of general physiology2018
Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of Ca
Open access · bronzeAbstract read
In one paragraph
Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Targeted Therapies for Skeletal Muscle Ion Channelopathies: Systematic Review and Steps Towards Precision Medicine.Journal of neuromuscular diseases · 2021Pooled it
- Molecular genetics of skeletal muscle diseases associated with abnormal excitation-contraction coupling.Journal of human genetics · 2026Review
- Pathological changes and therapeutic strategies for sarcopenia.EFORT open reviews · 2026Review
- STAC3 binding to CaV1.1 II-III loop is nonessential but critically supports skeletal muscle excitation-contraction coupling.JCI insight · 2025Article
- The molecular transition that confers voltage dependence to muscle contraction.Nature communications · 2025Article
- Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessiveeLife · 2023Article
- From α1s splicing to γ1 function: A new twist in subunit modulation of the skeletal muscle L-type Ca2+ channel.The Journal of general physiology · 2022Article
- Molecular interactions of STAC proteins with skeletal muscle dihydropyridine receptor and excitation-contraction coupling.Protein science : a publication of the Protein Society · 2022Article
- The Builders of the Junction: Roles of Junctophilin1 and Junctophilin2 in the Assembly of the Sarcoplasmic Reticulum-Plasma Membrane Junctions in Striated Muscle.Biomolecules · 2022Review
- Structural Insight Into Ryanodine Receptor Channelopathies.Frontiers in pharmacology · 2022Review
- Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle.Scientific reports · 2021Article
- Physiological and Pathological Relevance of Selective and Nonselective CaAdvances in experimental medicine and biology · 2021Article
- Skeletal muscle CaPflugers Archiv : European journal of physiology · 2020Review
- Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin.The Journal of general physiology · 2020Article
- Excitation-contraction coupling in skeletal muscle: recent progress and unanswered questions.Biophysical reviews · 2020Review
- Crystal structures of CaProceedings of the National Academy of Sciences of the United States of America · 2019Article
- The binding interactions that maintain excitation-contraction coupling junctions in skeletal muscle.The Journal of general physiology · 2019Article
- Dihydropyridine Receptor Congenital Myopathy In A Consangineous Turkish Family.Journal of neuromuscular diseases · 2019Article
- STAC3 incorporation into skeletal muscle triads occurs independent of the dihydropyridine receptor.Journal of cellular physiology · 2018Article
- Stac Proteins Suppress CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Alexander PolsterDepartment of Physiology and Biophysics, University of Colorado Denver, Aurora, CO.ORCID 0000-0003-2985-6518
Benjamin R NelsonDepartment of Molecular Biology, Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, TX.ORCID 0000-0003-0711-154X
Symeon PapadopoulosInstitute of Vegetative Physiology, University Hospital of Cologne, Cologne, Germany.ORCID 0000-0002-0708-7431
Eric N OlsonDepartment of Molecular Biology, Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, TX.
Kurt G BeamDepartment of Physiology and Biophysics, University of Colorado Denver, Aurora, CO kurt.beam@ucdenver.edu.ORCID 0000-0001-6902-085X
Southwestern Medical Center · USUniversity of Colorado Denver · USUniversity Hospital Cologne · DE
Funding
Uncovering the Molecular Basis of Malignant HyperthermiaP01AR052354 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RAMSEY, JON J. · 2006 to 2016
$13.4MMicroenvironmental control of progenitors in organ dysfunction and repairU01HL100401 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N, SCHNEIDER, JAY W · 2009 to 2015
$8.3MHeart Repair through Reprogramming of Cardiac Cell FateR01HL077439 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N · 2004 to 2015
$6.2MRegulation of Membrane ExcitabilityR01AR055104 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI BEAM, KURT G · 2008 to 2012
$3.1MMicroRNA Control of Cardiac Gene Expression, Function and DiseaseR01HL093039 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N · 2009 to 2013
$2.8MDeciphering a Regulatory Circuit for Myocardial Metabolism and Energy HomeostasisR01HL111665 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N · 2012 to 2015
$2.4MRegulation of Membrane ExcitabilityR01AR070298 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI BEAM, KURT G · 2016 to 2020
$2.0MMetabolic Control by Myogenic MicroRNAs, Mediator and MyokinesR01DK099653 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI BASSEL-DUBY, RHONDA, OLSON, ERIC N · 2013 to 2016
$1.9MNHLBI NIH HHS R01 HL077439NHLBI NIH HHS R01 HL093039NHLBI NIH HHS R01 HL111665NHLBI NIH HHS U01 HL100401NIAMS NIH HHS P01 AR052354NIAMS NIH HHS R01 AR055104NIAMS NIH HHS R01 AR070298NIDDK NIH HHS R01 DK099653
Abstract
In skeletal muscle, residues 720-764/5 within the Ca
Indexed as
Excitation Contraction CouplingAdaptor Proteins, Signal TransducingAnimalsBinding SitesCalcium Channels, L-TypeCalcium SignalingCell LineCells, CulturedHumansMiceMuscle Fibers, SkeletalNerve Tissue ProteinsProtein BindingRabbitsRyanodine Receptor Calcium Release ChannelAdaptor Proteins, Signal TransducingCACNA1S protein, mouseCalcium Channels, L-TypeNerve Tissue ProteinsRyanodine Receptor Calcium Release ChannelStac2 protein, mouseSTAC3 protein, mouseStac protein, mouse
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.