ArticleBMJ open2018
HIV/AIDS mortality attributable to alcohol use in South Africa: a comparative risk assessment by socioeconomic status.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of alcohol use disorders among people living with HIV/AIDS: a systematic review and meta-analysis.Substance abuse treatment, prevention, and policy · 2019Pooled it
- Efficacy of Behavioral Intervention, Text Messaging, and Extended Intervention to Address Alcohol Misuse in Sexual Minority Men with HIV: A Factorial Randomized Clinical Trial.AIDS and behavior · 2024Trial
- Increases in employment over six months following Khanya: A secondary analysis of a pilot randomized controlled trial of a peer-delivered behavioral intervention for substance use and HIV medication adherence in Cape Town, South Africa.The International journal on drug policy · 2024Trial
- Alcohol Use, HIV Stigma and Quality of Life Among Alcohol Consuming Men Living with HIV in India: A Mediation Analysis.AIDS and behavior · 2023Trial
- Gender Moderates Results of a Randomized Clinical Trial for the Khanya Intervention for Substance Use and ART Adherence in HIV Care in South Africa.AIDS and behavior · 2022Trial
- Socio-Demographic Factors Associated with Alcohol and Tobacco Use Among Virally Suppressed People Living with HIV in the Eastern Cape, South Africa.Tropical medicine and infectious disease · 2026Article
- The relationship between emotional dysregulation and, HIV acquisition risk behaviours and intimate partner violence perpetration among young men in rural areas and urban informal settlements in South Africa.Psychology, health & medicine · 2026Article
- Article
- Lab tests can be used to predict phosphatidylethanol-measured high-risk alcohol use among people with HIV: a proof-of-concept using machine learning.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Article
- Psychometric Validation of the East Africa Alcohol Expectancy Scale (AFEXS) for Youth Living with HIV in Southwestern Uganda.AIDS and behavior · 2025Article
- Validation of screening instruments for alcohol and substance use disorders among men and women in Eastern Cape, South Africa.Drug and alcohol dependence · 2025Article
- Alcohol Consumption and Health Outcomes Among Men in a Rural HIV-Endemic Cohort in South Africa.Wellcome open research · 2025Article
- Prevalence and Correlates of Substance Use Among Youth Living with HIV in Fishing Communities in Uganda.AIDS and behavior · 2024Article
- Symptoms of posttraumatic stress partially mediate the relationship between gender-based violence and alcohol misuse among South African women.Substance abuse treatment, prevention, and policy · 2023Article
- Assessing the Feasibility of Economic Approaches to Prevent Substance Abuse Among Adolescents: Protocol for a Mixed Methods Study.JMIR research protocols · 2023Article
- Social Determinants of Alcohol and Other Drug Misuse Among Women Living with HIV in Economically Underserved Communities in Cape Town, South Africa: A Cross-Sectional Study.AIDS and behavior · 2023Article
- Exploring Determinants of HIV/AIDS Self-Testing Uptake in South Africa Using Generalised Linear Poisson and Geographically Weighted Poisson Regression.Healthcare (Basel, Switzerland) · 2023Article
- Demographic and clinical characteristics associated with tobacco smoking and alcohol use disorder among heterosexual people living with HIV in West Papua, Indonesia.Journal of preventive medicine and hygiene · 2023Article
- Hazardous alcohol use and HIV indicators in six African countries: results from the Population-based HIV Impact Assessments, 2015-2017.Journal of the International AIDS Society · 2022Article
- Sex stratification of the trends and risk of mortality among individuals living with HIV under different transmission categories.Scientific reports · 2022Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo quantify HIV/AIDS mortality attributable to alcohol use in the adult general population of South Africa in 2012 by socioeconomic status (SES).
designComparative risk assessment based on secondary individual data, aggregate data and risk relations reported in the literature.
settingSouth African adult general population.
participantsFor metrics of alcohol use by SES, sex and age: 27 070 adults that participated in a nationally representative survey in 2012. For HRs of dying from HIV/AIDS by SES: 87 029 adults that participated in a cohort study (years 2000 to 2014) based out of the Umkhanyakude district, KwaZulu-Natal.
main outcome measuresAlcohol-attributable fractions for HIV/AIDS mortality by SES, age and sex were calculated based on the risk of engaging in condom-unprotected sex under the influence of alcohol and interactions between SES and alcohol use. Age-standardised HIV/AIDS mortality rates attributable to alcohol by SES and sex were estimated using alcohol-attributable fractions and SES-specific and sex-specific death counts. Rate ratios were calculated comparing age-standardised rates in low versus high SES by sex.
resultsThe age-standardised HIV/AIDS mortality rate attributable to alcohol was 31.0 (95% uncertainty interval (UI) 21.6 to 41.3) and 229.6 (95% UI 108.8 to 351.6) deaths per 100 000 adults for men of high and low SES, respectively. For women the respective rates were 10.8 (95% UI 5.5 to 16.1) and 75.5 (95% UI 31.2 to 144.9). The rate ratio was 7.4 (95% UI 3.4 to 13.2) for men and 7.0 (95% UI 2.8 to 18.2) for women. Sensitivity analyses corroborated marked differences in alcohol-attributable HIV/AIDS mortality, with rate ratios between 2.7 (95% UI 0.8 to 7.6; women) and 15.1 (95% UI 6.8 to 27.7; men).
conclusionsThe present study showed that alcohol use contributed considerably to the socioeconomic differences in HIV/AIDS mortality. Targeting HIV infection under the influence of alcohol is a promising strategy for interventions to reduce the HIV/AIDS burden and related socioeconomic differences in South Africa.
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