ArticleDiagnostic and interventional radiology (Ankara, Turkey)
The pancreatic and extrapancreatic manifestations of IgG4-related disease.
Article in Diagnostic and interventional radiology (Ankara, Turkey). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 26 citations in OpenAlex.
- Clinical Variability of Pediatric MERS: Insights from a Retrospective Observational Study.Journal of clinical medicine · 2025Article
- IgG4-related disease - focus on digestive system involvement.Frontiers in immunology · 2025Review
- Extra-pancreatic manifestations reported in association with pancreatitis; an international survey report.PloS one · 2023Article
- MRI Features in Submandibular Gland Chronic Sclerosing Sialadenitis: A Report of Three Cases and Imaging Findings.Iranian journal of otorhinolaryngology · 2020Article
- Imaging findings of IgG4-related kidney disease without extrarenal organ involvement: A case report.Medicine · 2019Article
- A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis.Journal of investigative medicine high impact case reportsArticle
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Authors and funding
5 authors at 1 institution in 4 countries.
Funding
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Abstract
The association between immunoglobulin IgG4 and autoimmune pancreatitis was first shown in 2001. Since then many previously established fibrosclerotic diseases demonstrating synchronous or metachronous multiorgan involvement have been included within the ambit of IgG4-related disease. Diagnostic criteria have been proposed involving 1) serum IgG4 level elevated beyond 135 mg/dL, 2) IgG4+ to IgG+ plasma cell ratio > 40% and >10 IgG4+ cells per high power field of biopsy sample and 3) a constellation of imaging features which involve a variety of organ systems. We present a pictorial essay demonstrating the spectrum of imaging findings for IgG4-related disease, including dacryosialadenitis, variety of renal lesions, tumefactive thickening of the extraocular muscles and orbital nerve, sclerosing cholangitis, and type I pancreatitis. Imaging plays an important role in diagnosis, screening for multiorgan involvement, and follow-up of the disease.
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